Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 264 | 726 | 2.75 | 132 | 50.00% | 86 | 32.58% | 46 | 17.42% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Toronto FC | 27 | 12 | 7 | 8 | 39 | 28 | +11 | 43 | LWWX | 12 | 7 | 3 | 2 | 20 | 9 | 15 | 5 | 4 | 6 | 19 | 19 | ||
| 2 | New York Red Bulls | 27 | 11 | 7 | 9 | 46 | 35 | +11 | 40 | WXWX | 13 | 10 | 1 | 2 | 27 | 11 | 14 | 1 | 6 | 7 | 19 | 24 | ||
| 3 | Philadelphia Union | 27 | 11 | 7 | 9 | 47 | 41 | +6 | 40 | WWLW | 14 | 8 | 3 | 3 | 29 | 19 | 13 | 3 | 4 | 6 | 18 | 22 | ||
| 4 | Montréal Impact | 26 | 9 | 10 | 7 | 40 | 38 | +2 | 37 | WXLL | 13 | 6 | 4 | 3 | 24 | 19 | 13 | 3 | 6 | 4 | 16 | 19 | ||
| 5 | D.C. United | 26 | 7 | 11 | 8 | 33 | 33 | +0 | 32 | WXXW | 14 | 6 | 4 | 4 | 25 | 16 | 12 | 1 | 7 | 4 | 8 | 17 | ||
| 6 | Orlando City | 26 | 6 | 13 | 7 | 41 | 44 | -3 | 31 | WLOX | 14 | 5 | 7 | 2 | 26 | 21 | 12 | 1 | 6 | 5 | 15 | 23 | ||
| 7 | New England Revolution | 27 | 6 | 9 | 12 | 29 | 47 | -18 | 27 | LOLL | 13 | 5 | 4 | 4 | 15 | 17 | 14 | 1 | 5 | 8 | 14 | 30 | ||
| 8 | 1 | Columbus Crew | 25 | 5 | 11 | 9 | 34 | 40 | -6 | 26 | WLWX | 14 | 4 | 8 | 2 | 25 | 22 | 11 | 1 | 3 | 7 | 9 | 18 | |
| 9 | 1 | Chicago Fire | 25 | 5 | 8 | 12 | 29 | 40 | -11 | 23 | LXWX | 12 | 4 | 6 | 2 | 16 | 14 | 13 | 1 | 2 | 10 | 13 | 26 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | FC Dallas | 27 | 14 | 6 | 7 | 42 | 35 | +7 | 48 | WLXW | 13 | 9 | 4 | 0 | 27 | 9 | 14 | 5 | 2 | 7 | 15 | 26 | ||
| 2 | 1 | Real Salt Lake | 27 | 12 | 7 | 8 | 39 | 37 | +2 | 43 | WWLW | 13 | 8 | 5 | 0 | 19 | 10 | 14 | 4 | 2 | 8 | 20 | 27 | |
| 3 | 1 | Colorado Rapids | 25 | 11 | 10 | 4 | 28 | 22 | +6 | 43 | LOXW | 13 | 9 | 4 | 0 | 16 | 5 | 12 | 2 | 6 | 4 | 12 | 17 | |
| 4 | LA Galaxy | 26 | 9 | 13 | 4 | 40 | 26 | +14 | 40 | OXLX | 13 | 6 | 7 | 0 | 24 | 11 | 13 | 3 | 6 | 4 | 16 | 15 | ||
| 5 | Sporting Kansas City | 28 | 11 | 5 | 12 | 32 | 32 | +0 | 38 | LWXL | 14 | 9 | 1 | 4 | 23 | 14 | 14 | 2 | 4 | 8 | 9 | 18 | ||
| 6 | Portland Timbers | 27 | 9 | 8 | 10 | 41 | 41 | +0 | 35 | WLLW | 14 | 9 | 2 | 3 | 31 | 20 | 13 | 0 | 6 | 7 | 10 | 21 | ||
| 7 | San Jose Earthquakes | 26 | 7 | 11 | 8 | 26 | 29 | -3 | 32 | LOLW | 13 | 6 | 5 | 2 | 14 | 8 | 13 | 1 | 6 | 6 | 12 | 21 | ||
| 8 | Seattle Sounders | 26 | 9 | 4 | 13 | 32 | 36 | -4 | 31 | LXWW | 13 | 7 | 1 | 5 | 18 | 11 | 13 | 2 | 3 | 8 | 14 | 25 | ||
| 9 | Vancouver Whitecaps | 27 | 8 | 7 | 12 | 34 | 43 | -9 | 31 | OLLL | 13 | 5 | 5 | 3 | 20 | 15 | 14 | 3 | 2 | 9 | 14 | 28 | ||
| 10 | Houston Dynamo | 26 | 5 | 10 | 11 | 29 | 34 | -5 | 25 | LXWX | 13 | 4 | 7 | 2 | 18 | 14 | 13 | 1 | 3 | 9 | 11 | 20 | ||
| 16 | +1 | Bradley WRIGHT-PHILLIPS (New York Red Bulls) |
| David VILLA (New York City, 4p) | ||
| Sebastian GIOVINCO (Toronto FC, 3p) | ||
| 14 | +1 | Ignacio PIATTI (Montréal Impact, 2p) |
| 13 | +1 | Fanendo ADI (Portland Timbers, 1p) |
| Cyle LARIN (Orlando City) | ||
| 12 | Dominic DWYER (Sporting Kansas City) | |
| 10 | Chris PONTIUS (Philadelphia Union) | |
| Ola KAMARA (Columbus Crew, 1p) | ||
| Diego VALERI (Portland Timbers, 3p) | ||
| 9 | Kei KAMARA (New England Revolution, 1p) | |
| Chris WONDOLOWSKI (San Jose Earthquakes, 2p) | ||
| Frank LAMPARD (New York City, 1p) | ||
| +1 | Jordan MORRIS (Seattle Sounders) | |
| +1 | Roland ALBERG (Philadelphia Union, 4p) | |
| Kevin MOLINO (Orlando City, 1p) | ||
| +2 | Yura MOVSISYAN (Real Salt Lake, 2p) | |
| GIOVANI dos Santos (LA Galaxy) | ||
| 8 | Clint DEMPSEY (Seattle Sounders, 2p) | |
| +2 | Michael BARRIOS (FC Dallas) | |
| Didier DROGBA (Montréal Impact, 1p) |
| Friday, 26 August 2016 | |||||
| Real Salt Lake | 2-1 | Colorado Rapids | |||
| 39 | Movsisyan | 5 | Gashi | ||
| 48 | Movsisyan | ||||
| Saturday, 27 August 2016 | |||||
| D.C. United | 6-2 | Chicago Fire | |||
| 25 | Acosta | 31 | De Leeuw | ||
| 40 | Mullins | 45 | Cociș | ||
| 45 | Mullins | ||||
| 51 | Nyarko | ||||
| 74 | Mullins | ||||
| 89 | Deleon | ||||
| Houston Dynamo | 1-3 | FC Dallas | |||
| 19 | Alex Lima | 59(p) | Díaz | ||
| 60 | Barrios | ||||
| 79 | Barrios | ||||
| Columbus Crew | 2-0 | San Jose Earthquakes | |||
| 32 | Finlay | ||||
| 84(p) | Meram | ||||
| LA Galaxy | 0-0 | Vancouver Whitecaps | |||
| Toronto FC | 0-1 | Montréal Impact | |||
| 73 | Piatti | ||||
| Philadelphia Union | 2-0 | Sporting Kansas City | |||
| 67 | Alberg | ||||
| 90 | Barnetta | ||||
| Sunday, 28 August 2016 | |||||
| New York Red Bulls | 1-0 | New England Revolution | |||
| 55 | Wright-Phillips | ||||
| Portland Timbers | 4-2 | Seattle Sounders | |||
| 16 | Andriuškevičius | 47 | Ivanschitz | ||
| 21 | Adi | 51 | Morris | ||
| 29 | Melano | ||||
| 44 | Taylor | ||||
| Orlando City | 2-1 | New York City | |||
| 32 | Kaká | 55 | Mendoza | ||
| 63(p) | Kaká | ||||
