MLS is Back| ROUND | G | R2 | QF | SF | F | ||
| r1 | r2 | r3 | |||||
| Group A | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 |  | Orlando City | 3 | 2 | 1 | 0 | 6 | 3 | +3 | 7 | XWW- | |
| 2 | | Philadelphia Union | 3 | 2 | 1 | 0 | 4 | 2 | +2 | 7 | XWW- | |
| 3 |  1 | New York City | 3 | 1 | 0 | 2 | 2 | 4 | -2 | 3 | WLL- | |
| 4 |  1 | Inter Miami | 3 | 0 | 0 | 3 | 2 | 5 | -3 | 0 | LLL- | |
| Monday, 20 July 2020 | |||||
| 3 | Philadelphia Union | 1-1 | Orlando City | ||
| 68 | Ilsinho | 70 | Pereyra | ||
| 3 | Inter Miami | 0-1 | New York City | ||
| 64 | Tajouri | ||||
| Group B | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | San Jose Earthquakes | 3 | 2 | 1 | 0 | 6 | 3 | +3 | 7 | WWO- | |
| 2 | 2 | Seattle Sounders | 3 | 1 | 1 | 1 | 4 | 2 | +2 | 4 | WLO- | |
| 3 | 1 | Vancouver Whitecaps | 3 | 1 | 0 | 2 | 5 | 7 | -2 | 3 | LLW- | |
| 4 | 1 | Chicago Fire | 3 | 1 | 0 | 2 | 2 | 5 | -3 | 3 | LWL- | |
| Sunday, 19 July 2020 | |||||
| 3 | Chicago Fire | 0-2 | San Jose Earthquakes | ||
| 56 | Espinoza | ||||
| 83 | Wondolowski | ||||
| 3 | Seattle Sounders | 3-0 | Vancouver Whitecaps | ||
| 16(p) | Lodeiro | ||||
| 34 | Morris | ||||
| 51 | Ruidíaz | ||||
| Group C | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Toronto FC | 3 | 1 | 2 | 0 | 6 | 5 | +1 | 5 | OWX- | |
| 2 | | New England Revolution | 3 | 1 | 2 | 0 | 2 | 1 | +1 | 5 | OXW- | |
| 3 | 1 | Montréal Impact | 3 | 1 | 0 | 2 | 4 | 5 | -1 | 3 | WLL- | |
| 4 | 1 | D.C. United | 3 | 0 | 2 | 1 | 3 | 4 | -1 | 2 | LXX- | |
| Tuesday, 21 July 2020 | |||||
| 3 | Montréal Impact | 1-0 | D.C. United | ||
| 31 | Taïder | ||||
| 3 | Toronto FC | 0-0 | New England Revolution | ||
| Group D | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | 2 | Sporting Kansas City | 3 | 2 | 0 | 1 | 6 | 4 | +2 | 6 | WWL- | |
| 2 | | Minnesota United | 3 | 1 | 2 | 0 | 4 | 3 | +1 | 5 | XOW- | |
| 3 | 2 | Real Salt Lake | 3 | 1 | 1 | 1 | 2 | 2 | +0 | 4 | LOW- | |
| 4 | | Colorado Rapids | 3 | 0 | 1 | 2 | 4 | 7 | -3 | 1 | XLL- | |
| Wednesday, 22 July 2020 | |||||
| 3 | Colorado Rapids | 2-2 | Minnesota United | ||
| 19 | Kamara | 36 | Finlay | ||
| 59 | Lewis | 43 | Finlay | ||
| 3 | Real Salt Lake | 0-2 | Sporting Kansas City | ||
| 1 | Russell | ||||
| 86 | Gerso | ||||
| Group E | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Columbus Crew | 3 | 3 | 0 | 0 | 7 | 0 | +7 | 9 | WWW- | |
| 2 | 1 | FC Cincinnati | 3 | 2 | 0 | 1 | 3 | 4 | -1 | 6 | WWL- | |
| 3 | 1 | New York | 3 | 1 | 0 | 2 | 1 | 4 | -3 | 3 | LLW- | |
| 4 | | Atlanta United | 3 | 0 | 0 | 3 | 0 | 3 | -3 | 0 | LLL- | |
| Tuesday, 21 July 2020 | |||||
| 3 | Atlanta United | 0-1 | Columbus Crew | ||
| 18 | Mokhtar | ||||
| Wednesday, 22 July 2020 | |||||
| 3 | FC Cincinnati | 2-0 | New York | ||
| 43 | Kubo | ||||
| 56(og) | Valot | ||||
| Group F | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Portland Timbers | 3 | 2 | 1 | 0 | 6 | 4 | +2 | 7 | XWW- | |
| 2 | | Los Angeles | 3 | 1 | 2 | 0 | 11 | 7 | +4 | 5 | XWX- | |
| 3 | | Houston Dynamo | 3 | 0 | 2 | 1 | 5 | 6 | -1 | 2 | XLX- | |
| 4 | | LA Galaxy | 3 | 0 | 1 | 2 | 4 | 9 | -5 | 1 | XLL- | |
| Thursday, 23 July 2020 | |||||
| 3 | LA Galaxy | 1-1 | Houston Dynamo | ||
| 90(p) | Pavón | 17 | Quintero | ||
| 3 | Los Angeles | 2-2 | Portland Timbers | ||
| 36 | Wright-Phillips | 7 | Niezgoda | ||
| 40 | Kaye | 81 | Ebobisse | ||
| 5 | Diego ROSSI (Los Angeles, 1p) | |
| Ayo AKINOLA (Toronto FC) | ||
| 3 | Chris MUELLER (Orlando City) | |
| +1 | Jeremy EBOBISSE (Portland Timbers) | |
| +1 | Bradley WRIGHT-PHILLIPS (Los Angeles) | |
| Gyasi ZARDES (Columbus Crew) | ||
| +1 | Saphir TAÏDER (Montréal Impact, 2p) | |
| 2 | +1 | Cristian PAVÓN (LA Galaxy, 2p) |
| Cristian DÁJOME (Vancouver Whitecaps) | ||
| Lucas ZELARAYÁN (Columbus Crew) | ||
| +1 | Chris WONDOLOWSKI (San Jose Earthquakes) | |
| Memo RODRIGUEZ (Houston Dynamo) | ||
| +1 | Jonathan LEWIS (Colorado Rapids) | |
| Khiry SHELTON (Sporting Kansas City) | ||
| Alberth ELIS (Houston Dynamo, 1p) | ||
| +1 | Youness MOKHTAR (Columbus Crew) | |
| Federico HIGUAÍN (D.C. United) | ||
| +2 | Ethan FINLAY (Minnesota United) |
