| ROUND | R1 | R2 | R3 | QF | SF | F | ||||
| l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | |||
| Season archive |
| Tuesday, 28 June 2022 | ||||||
| r3l1 |  Nacional | 2-0 | Unión | |||
| r3l1 |  Colo Colo | 2-0 | Internacional | |||
| Wednesday, 29 June 2022 | ||||||
| r3l1 |  Strongest | 1-2 | Ceará | |||
| r3l1 |  Cali | 0-0 | FBC Melgar | |||
| r3l1 |  Deportivo Táchira | 1-1 | Santos | |||
| Thursday, 30 June 2022 | ||||||
| r3l1 |  Olimpia | 2-0 | Atlético-GO | |||
| r3l1 | Universidad Católica | 2-4 | São Paulo | |||
| r3l1 |  Independiente | 2-1 | Lanús | |||
| Tuesday, 5 July 2022 | ||||||
| r3l2 | Internacional | 4-1 | Colo Colo | 4-3 | ||
| r3l2 | Unión | 1-2 | Nacional | 1-4 | ||
| Wednesday, 6 July 2022 | ||||||
| r3l2 | Santos | 1-1 | Deportivo Táchira | 2-2, p2-4 | ||
| r3l2 | Ceará | 3-0 | Strongest | 5-1 | ||
| r3l2 | FBC Melgar | 2-1 | Cali | 2-1 | ||
| Thursday, 7 July 2022 | ||||||
| r3l2 | São Paulo | 4-1 | Universidad Católica | 8-3 | ||
| r3l2 | Lanús | 0-0 | Independiente | 1-2 | ||
| r3l2 | Atlético-GO | 2-0 | Olimpia | 2-2, p5-3 | ||
| 8 | +2 | Bernardo CUESTA (FBC Melgar, 2p) |
| 5 | Stiven MENDOZA (Ceará, 1p) | |
| Miguel BORJA (Junior, 2p) | ||
| Mario OTAZÚ (Guaireña, 2p) | ||
| 4 | +3 | LUCIANO da Rocha (São Paulo, 1p) |
| Sebastián SÁEZ (Unión La Calera) | ||
| Alexander ALVARADO (LDU Quito) | ||
| Mauro MÉNDEZ (Wanderers) | ||
| Cristian TECHERA (Ayacucho FC, 1p) | ||
| Lucas ALBERTENGO (Defensa y Justicia) | ||
| 3 | Leandro BENEGAS (Independiente) | |
| Germán CANO (Fluminense) | ||
| Nilson ANGULO (LDU Quito) | ||
| RODRIGO DOURADO Cunha (Internacional) | ||
| Alfredo STEPHENS (9 de Octubre, 1p) | ||
| Manuel LÓPEZ (Antofagasta) | ||
| MATHEUS MARTINS Silva (Fluminense) | ||
| +1 | EDENÍLSON Andrade (Internacional) | |
| +1 | ERICK de Arruda (Ceará, 1p) | |
| José SAND (Lanús) | ||
| +1 | Brayan ANGULO (Santos) | |
| Mauro DA LUZ (9 de Octubre) | ||
| Facundo SUÁREZ (Oriente Petrolero) |
