Results| Sunday, 30 November 2025 |
| 22 | Comunicaciones | 0-1 | Xelajú |
| |
| 32 | Cardenas |
| 22 | Aurora | 1-0 | Mixco |
| 73 | Galindo |
| |
| 22 | Marquense | 0-2 | Municipal |
| |
| 22 | Hernández |
|
| 40 | Bantes |
| 22 | Achuapa | 1-1 | Guastatoya |
| 21 | Maziero |
| 34 | Ávalos |
| 22 | Cobán Imperial | 0-0 | Mictlán |
| 22 | Antigua | 2-0 | Malacateco |
| 14 | Fernández |
| |
| 83 | Macareño |
| |
| Play-offs |
| Saturday, 6 December 2025 |
| qfl1 | Mictlán | 0-1 | Municipal |
| |
| 90 | Hernández |
| qfl1 | Malacateco | 1-0 | Aurora |
| 38 | Angulo |
| |
| Sunday, 7 December 2025 |
| qfl1 | Achuapa | 3-2 | Mixco |
| 19(p) | Maziero |
| 8 | Pozuelos |
| 41 | Sánchez |
| 47 | Martínez |
| 59 | Castrillo |
| |
| Monday, 8 December 2025 |
| qfl1 | Xelajú | 1-0 | Antigua |
| 68(p) | López |
| |
| Wednesday, 10 December 2025 |
| qfl2 | Municipal | 2-0 | Mictlán | 3-0 |
| 15 | Calderón |
| |
| 58 | Hernández |
| |
| qfl2 | Aurora | 2-1 | Malacateco | 2-2 |
| 6 | Galindo |
| 40 | López |
| 63 | Lovato |
| |
| Thursday, 11 December 2025 |
| qfl2 | Antigua | 2-0 | Xelajú | 2-1 |
| 79 | Castañeda |
| |
| 90 | Macareño |
| |
| qfl2 | Mixco | 0-0 | Achuapa | 2-3 |
| Sunday, 14 December 2025 |
| sfl1 | Aurora | 0-1 | Antigua |
| |
| 73 | Prillwitz |
| sfl1 | Achuapa | 1-1 | Municipal |
| 41 | Maziero |
| 7 | Muñoz |
| Wednesday, 17 December 2025 |
| sfl2 | Antigua | 4-2 | Aurora | 5-2 |
| 7 | Santis |
| 12 | Galindo |
| 28 | Castellanos |
| 81 | Álvarez |
| 57 | Bradley |
| |
| 70 | Prillwitz |
| |
| Thursday, 18 December 2025 |
| sfl2 | Municipal | 3-0 | Achuapa | 4-1 |
| 28 | Martinez |
| |
| 33 | Muñoz |
| |
| 38 | Pérez |
| |
| Sunday, 21 December 2025 |
| fl1 | Antigua | 2-0 | Municipal |
| 41 | Apaolaza |
| |
| 78(p) | Santis |
| |
| Saturday, 27 December 2025 |
| fl2 | Municipal | 1-0 | Antigua | 1-2 |
| 10 | Calderón |
| |
| Tuesday, 20 January 2026 |
| 1 | Xelajú | - | Aurora |
|
| Wednesday, 21 January 2026 |
| 1 | Malacateco | - | Marquense |
|
| 1 | Achuapa | - | Comunicaciones |
|
| 1 | Cobán Imperial | - | Antigua |
|
| Thursday, 22 January 2026 |
| 1 | Municipal | - | Mictlán |
|
| 1 | Guastatoya | - | Mixco |
|
| Saturday, 24 January 2026 |
| 2 | Comunicaciones | - | Cobán Imperial |
|
| 2 | Marquense | - | Achuapa |
|
| Sunday, 25 January 2026 |
| 2 | Aurora | - | Municipal |
|
| 2 | Mictlán | - | Guastatoya |
|
| 2 | Antigua | - | Xelajú |
|
| 2 | Mixco | - | Malacateco |
|
| Tuesday, 27 January 2026 |
| 3 | Cobán Imperial | - | Marquense |
|
| Wednesday, 28 January 2026 |
| 3 | Municipal | - | Xelajú |
|
| 3 | Achuapa | - | Mixco |
|
| 3 | Antigua | - | Comunicaciones |
|
| 3 | Guastatoya | - | Aurora |
|
| Thursday, 29 January 2026 |
| 3 | Malacateco | - | Mictlán |
|
| Saturday, 31 January 2026 |
| 4 | Municipal | - | Guastatoya |
|
| 4 | Marquense | - | Antigua |
|
| 4 | Xelajú | - | Comunicaciones |
|
| 4 | Mixco | - | Cobán Imperial |
|
| Sunday, 1 February 2026 |
| 4 | Aurora | - | Malacateco |
|
| 4 | Mictlán | - | Achuapa |
|
| Friday, 6 February 2026 |
| 5 | Malacateco | - | Municipal |
|
| Saturday, 7 February 2026 |
| 5 | Comunicaciones | - | Marquense |
|
| 5 | Achuapa | - | Aurora |
|
| 5 | Guastatoya | - | Xelajú |
|
| Sunday, 8 February 2026 |
| 5 | Cobán Imperial | - | Mictlán |
|
| 5 | Antigua | - | Mixco |
|
| Saturday, 14 February 2026 |
| 6 | Municipal | - | Achuapa |
|
| 6 | Mixco | - | Comunicaciones |
|
| 6 | Guastatoya | - | Malacateco |
|
| Sunday, 15 February 2026 |
| 6 | Aurora | - | Cobán Imperial |
|
| 6 | Xelajú | - | Marquense |
|
| 6 | Mictlán | - | Antigua |
|
Liga Nacional
