Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 154 | 414 | 2.68 | 79 | 51.30% | 41 | 26.62% | 34 | 22.08% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 22 | 12 | 4 | 6 | 36 | 29 | +7 | 40 | WWWL | 11 | 7 | 2 | 2 | 21 | 14 | 11 | 5 | 2 | 4 | 15 | 15 | ||
| 2 | New England Revolution | 22 | 11 | 5 | 6 | 31 | 29 | +2 | 38 | XXWL | 11 | 5 | 3 | 3 | 17 | 14 | 11 | 6 | 2 | 3 | 14 | 15 | ||
| 3 | Chicago Fire | 22 | 10 | 5 | 7 | 29 | 18 | +11 | 35 | LWLW | 10 | 4 | 2 | 4 | 11 | 8 | 12 | 6 | 3 | 3 | 18 | 10 | ||
| 4 | D.C. United | 22 | 10 | 2 | 10 | 36 | 34 | +2 | 32 | OWLW | 12 | 8 | 1 | 3 | 28 | 13 | 10 | 2 | 1 | 7 | 8 | 21 | ||
| 5 | New York Red Bulls | 22 | 8 | 8 | 6 | 28 | 28 | +0 | 32 | OWWW | 11 | 7 | 3 | 1 | 20 | 10 | 11 | 1 | 5 | 5 | 8 | 18 | ||
| 6 | Toronto FC | 22 | 7 | 5 | 10 | 23 | 29 | -6 | 26 | LXLW | 11 | 5 | 5 | 1 | 11 | 5 | 11 | 2 | 0 | 9 | 12 | 24 | ||
| 7 | Kansas City Wizards | 22 | 6 | 8 | 8 | 23 | 30 | -7 | 26 | LXLW | 10 | 5 | 3 | 2 | 13 | 12 | 12 | 1 | 5 | 6 | 10 | 18 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Houston Dynamo | 22 | 9 | 8 | 5 | 31 | 26 | +5 | 35 | WLWW | 11 | 7 | 3 | 1 | 22 | 12 | 11 | 2 | 5 | 4 | 9 | 14 | ||
| 2 | Real Salt Lake | 22 | 8 | 6 | 8 | 27 | 27 | +0 | 30 | WLLW | 12 | 7 | 5 | 0 | 20 | 7 | 10 | 1 | 1 | 8 | 7 | 20 | ||
| 3 | 3 | Chivas USA | 22 | 7 | 6 | 9 | 28 | 32 | -4 | 27 | WOLX | 12 | 6 | 3 | 3 | 17 | 11 | 10 | 1 | 3 | 6 | 11 | 21 | |
| 4 | 1 | FC Dallas | 22 | 6 | 8 | 8 | 30 | 29 | +1 | 26 | LXLW | 11 | 4 | 4 | 3 | 17 | 15 | 11 | 2 | 4 | 5 | 13 | 14 | |
| 5 | LA Galaxy | 22 | 6 | 7 | 9 | 42 | 45 | -3 | 25 | XLXL | 11 | 4 | 3 | 4 | 23 | 19 | 11 | 2 | 4 | 5 | 19 | 26 | ||
| 6 | 1 | San Jose Earthquakes | 22 | 6 | 7 | 9 | 21 | 26 | -5 | 25 | WOWW | 10 | 4 | 3 | 3 | 15 | 13 | 12 | 2 | 4 | 6 | 6 | 13 | |
| 7 | 3 | Colorado Rapids | 22 | 7 | 3 | 12 | 29 | 32 | -3 | 24 | LLWL | 11 | 6 | 1 | 4 | 17 | 9 | 11 | 1 | 2 | 8 | 12 | 23 | |
| 16 | +2 | Landon DONOVAN (LA Galaxy, 3p) |
| 13 | Kenny COOPER (FC Dallas, 2p) | |
| 12 | Edson BUDDLE (LA Galaxy) | |
| 11 | Luciano EMILIO (D.C. United) | |
| 9 | Brian CHING (Houston Dynamo) | |
| Jaime MORENO (D.C. United, 4p) | ||
| 8 | +1 | Alejandro MORENO (Columbus Crew) |
| Juan Pablo ÁNGEL (New York Red Bulls) | ||
| 7 | Chad BARRETT (Toronto FC) | |
| 6 | Adam CRISTMAN (New England Revolution) | |
| Steve RALSTON (New England Revolution, 1p) | ||
| 5 | Robbie ROGERS (Columbus Crew) | |
| Jimmy CONRAD (Kansas City Wizards) | ||
| Guillermo BARROS SCHELOTTO (Columbus Crew, 4p) | ||
| John THORRINGTON (Chicago Fire) | ||
| +1 | Arturo ÁLVAREZ (San Jose Earthquakes) | |
| +1 | Taylor TWELLMAN (New England Revolution) | |
| +2 | Edgar ESPÍNDOLA (Real Salt Lake) | |
| +1 | Dwayne DE ROSARIO (Houston Dynamo, 1p) | |
| Danny DICHIO (Toronto FC) | ||
| Dave VAN DEN BERGH (New York Red Bulls) | ||
| Sacha KLJESTAN (Chivas USA) | ||
| Robbie FINDLEY (Real Salt Lake) | ||
| David BECKHAM (LA Galaxy) | ||
| Dominic ODURO (FC Dallas) | ||
| +1 | Jeff CUNNINGHAM (FC Dallas) | |
| Conor CASEY (Colorado Rapids) |
| Friday, 29 August 2008 | |||||
| Real Salt Lake | 2-0 | Colorado Rapids | |||
| 23 | Espíndola | ||||
| 59 | Espíndola | ||||
| Saturday, 30 August 2008 | |||||
| D.C. United | 0-0 | New York Red Bulls | |||
| FC Dallas | 1-2 | Columbus Crew | |||
| 35 | Cunningham | 37 | Moreno | ||
| 40 | Gaven | ||||
| New England Revolution | 2-2 | LA Galaxy | |||
| 22 | Twellman | 34 | Donovan | ||
| 71 | Joseph | 55 | Donovan | ||
| Chivas USA | 2-1 | Toronto FC | |||
| 20 | Eskandarian | 19 | Brennan | ||
| 90 | Harris | ||||
| San Jose Earthquakes | 2-1 | Kansas City Wizards | |||
| 43 | Álvarez | 64 | Arnaud | ||
| 83 | Huckerby | ||||
| Sunday, 31 August 2008 | |||||
| Houston Dynamo | 2-1 | Chicago Fire | |||
| 7 | De Rosario | 6 | McBride | ||
| 39 | Mullan | ||||
