Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 101 | 281 | 2.78 | 55 | 54.46% | 29 | 28.71% | 17 | 16.83% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Montréal Impact | 10 | 4 | 3 | 3 | 17 | 15 | +2 | 15 | XXXL | 4 | 2 | 1 | 1 | 7 | 4 | 6 | 2 | 2 | 2 | 10 | 11 | ||
| 2 | Philadelphia Union | 9 | 4 | 2 | 3 | 13 | 10 | +3 | 14 | XXWL | 5 | 3 | 2 | 0 | 10 | 4 | 4 | 1 | 0 | 3 | 3 | 6 | ||
| 3 | Toronto FC | 9 | 4 | 2 | 3 | 10 | 7 | +3 | 14 | WLWW | 1 | 1 | 0 | 0 | 1 | 0 | 8 | 3 | 2 | 3 | 9 | 7 | ||
| 4 | Orlando City | 9 | 2 | 5 | 2 | 16 | 14 | +2 | 11 | XXLX | 5 | 1 | 4 | 0 | 10 | 7 | 4 | 1 | 1 | 2 | 6 | 7 | ||
| 5 | 2 | New York Red Bulls | 10 | 3 | 1 | 6 | 13 | 18 | -5 | 10 | XWWL | 5 | 3 | 0 | 2 | 11 | 9 | 5 | 0 | 1 | 4 | 2 | 9 | |
| 6 | 1 | D.C. United | 10 | 2 | 4 | 4 | 11 | 13 | -2 | 10 | LXWL | 6 | 2 | 1 | 3 | 8 | 7 | 4 | 0 | 3 | 1 | 3 | 6 | |
| 7 | 1 | New England Revolution | 11 | 1 | 7 | 3 | 13 | 20 | -7 | 10 | LXXL | 5 | 1 | 4 | 0 | 5 | 4 | 6 | 0 | 3 | 3 | 8 | 16 | |
| 8 | Columbus Crew | 9 | 2 | 3 | 4 | 11 | 14 | -3 | 9 | XLWW | 4 | 2 | 1 | 1 | 9 | 8 | 5 | 0 | 2 | 3 | 2 | 6 | ||
| 9 | Chicago Fire | 8 | 1 | 4 | 3 | 8 | 10 | -2 | 7 | LXLO | 5 | 1 | 2 | 2 | 6 | 7 | 3 | 0 | 2 | 1 | 2 | 3 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Colorado Rapids | 11 | 7 | 2 | 2 | 14 | 8 | +6 | 23 | WWXW | 6 | 6 | 0 | 0 | 9 | 2 | 5 | 1 | 2 | 2 | 5 | 6 | ||
| 2 | 1 | FC Dallas | 12 | 6 | 2 | 4 | 17 | 19 | -2 | 20 | WLLL | 6 | 4 | 2 | 0 | 11 | 5 | 6 | 2 | 0 | 4 | 6 | 14 | |
| 3 | 1 | LA Galaxy | 10 | 5 | 4 | 1 | 24 | 12 | +12 | 19 | XWXW | 5 | 4 | 1 | 0 | 17 | 7 | 5 | 1 | 3 | 1 | 7 | 5 | |
| 4 | 1 | San Jose Earthquakes | 11 | 5 | 3 | 3 | 15 | 14 | +1 | 18 | WLXW | 6 | 5 | 1 | 0 | 10 | 3 | 5 | 0 | 2 | 3 | 5 | 11 | |
| 5 | 3 | Real Salt Lake | 9 | 5 | 2 | 2 | 14 | 13 | +1 | 17 | LWLW | 4 | 4 | 0 | 0 | 6 | 2 | 5 | 1 | 2 | 2 | 8 | 11 | |
| 6 | 2 | Vancouver Whitecaps | 12 | 5 | 2 | 5 | 16 | 17 | -1 | 17 | WWLX | 7 | 4 | 2 | 1 | 11 | 6 | 5 | 1 | 0 | 4 | 5 | 11 | |
| 7 | 1 | Sporting Kansas City | 12 | 4 | 2 | 6 | 11 | 13 | -2 | 14 | LLXX | 5 | 2 | 1 | 2 | 6 | 6 | 7 | 2 | 1 | 4 | 5 | 7 | |
| 8 | 1 | Seattle Sounders | 9 | 4 | 1 | 4 | 10 | 10 | +0 | 13 | WWLW | 6 | 4 | 0 | 2 | 7 | 4 | 3 | 0 | 1 | 2 | 3 | 6 | |
| 9 | 2 | Portland Timbers | 11 | 3 | 3 | 5 | 16 | 20 | -4 | 12 | LLWX | 5 | 3 | 1 | 1 | 10 | 8 | 6 | 0 | 2 | 4 | 6 | 12 | |
| 10 | Houston Dynamo | 10 | 2 | 2 | 6 | 17 | 19 | -2 | 8 | LWLL | 5 | 2 | 2 | 1 | 12 | 8 | 5 | 0 | 0 | 5 | 5 | 11 | ||
| 7 | Fanendo ADI (Portland Timbers, 1p) | |
| Chris WONDOLOWSKI (San Jose Earthquakes, 2p) | ||
| +1 | David VILLA (New York City, 2p) | |
| 6 | +2 | Ignacio PIATTI (Montréal Impact) |
| Sebastian GIOVINCO (Toronto FC, 2p) | ||
| 5 | +2 | Kei KAMARA (Columbus Crew, 1p) |
| +1 | GIOVANI dos Santos (LA Galaxy) | |
| 4 | +1 | Kennedy IGBOANANIKE (Chicago Fire) |
| Chris PONTIUS (Philadelphia Union) | ||
| Dominic DWYER (Sporting Kansas City) | ||
| +2 | Robbie KEANE (LA Galaxy, 2p) | |
| Cyle LARIN (Orlando City) | ||
| +1 | Jordan MORRIS (Seattle Sounders) | |
| +1 | Kevin MOLINO (Orlando City, 1p) | |
| Gyasi ZARDES (LA Galaxy) | ||
| +1 | Mike MAGEE (LA Galaxy) | |
| Michael BARRIOS (FC Dallas) | ||
| C.J. SAPONG (Philadelphia Union) | ||
| +1 | Dominic ODURO (Montréal Impact) | |
| Pedro MORALES (Vancouver Whitecaps, 4p) | ||
| Joao PLATA (Real Salt Lake, 1p) |
| Friday, 6 May 2016 | |||||
| Orlando City | 1-1 | New York Red Bulls | |||
| 67 | Molino | 19 | Wright-Phillips | ||
| Saturday, 7 May 2016 | |||||
| Houston Dynamo | 2-0 | Sporting Kansas City | |||
| 30 | Barnes | ||||
| 45 | Wenger | ||||
| Colorado Rapids | 1-0 | Real Salt Lake | |||
| 47 | Jones | ||||
| Columbus Crew | 4-4 | Montréal Impact | |||
| 16 | Kamara | 26 | Piatti | ||
| 45 | Kamara | 57(p) | Drogba | ||
| 48 | Higuaín | 58 | Piatti | ||
| 53(p) | Higuaín | 90 | Oduro | ||
| Vancouver Whitecaps | 2-1 | Portland Timbers | |||
| 60 | Kudo | 34 | Borchers | ||
| 66 | Bolaños | ||||
| Seattle Sounders | 2-0 | San Jose Earthquakes | |||
| 26 | Dempsey | ||||
| 89 | Morris | ||||
| Toronto FC | 1-0 | FC Dallas | |||
| 28 | Endoh | ||||
| Sunday, 8 May 2016 | |||||
| D.C. United | 0-2 | New York City | |||
| 49 | Villa | ||||
| 53 | Shelton | ||||
| LA Galaxy | 4-2 | New England Revolution | |||
| 13 | Keane | 67 | Rowe | ||
| 24 | Giovani | 70 | Agudelo | ||
| 45 | Keane | ||||
| 90 | Gerrard | ||||
| Wednesday, 11 May 2016 | |||||
| FC Dallas | 2-1 | Portland Timbers | |||
| 55 | Hollingshead | 3 | Valeri | ||
| 57 | Zimmerman | ||||
| Colorado Rapids | 1-0 | Sporting Kansas City | |||
| 78 | Serna | ||||
| Vancouver Whitecaps | 2-1 | Chicago Fire | |||
| 36 | Pérez | 62 | Igboananike | ||
| 89 | Pérez | ||||
| San Jose Earthquakes | 3-1 | Houston Dynamo | |||
| 3 | Quintero | 43 | Clark | ||
| 50 | Godoy | ||||
| 70 | Quintero | ||||
| Philadelphia Union | 2-2 | LA Galaxy | |||
| 4 | Nogueira | 15 | Rogers | ||
| 63 | Rosenberry | 47 | Magee | ||
