| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 257 | 756 | 2.94 | 143 | 55.64% | 59 | 22.96% | 55 | 21.40% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Toronto FC | 24 | 13 | 8 | 3 | 46 | 24 | +22 | 47 | WXWX | 12 | 9 | 3 | 0 | 30 | 8 | 12 | 4 | 5 | 3 | 16 | 16 | ||
| 2 | Chicago Fire | 23 | 12 | 5 | 6 | 45 | 28 | +17 | 41 | LWLL | 11 | 10 | 1 | 0 | 31 | 5 | 12 | 2 | 4 | 6 | 14 | 23 | ||
| 3 | New York Red Bulls | 23 | 12 | 2 | 9 | 37 | 30 | +7 | 38 | WLWW | 12 | 8 | 2 | 2 | 23 | 10 | 11 | 4 | 0 | 7 | 14 | 20 | ||
| 4 | 1 | Columbus Crew | 25 | 11 | 2 | 12 | 37 | 40 | -3 | 35 | WLXL | 12 | 8 | 1 | 3 | 24 | 13 | 13 | 3 | 1 | 9 | 13 | 27 | |
| 5 | 1 | Atlanta United | 22 | 10 | 5 | 7 | 42 | 29 | +13 | 35 | XXWW | 9 | 6 | 1 | 2 | 22 | 11 | 13 | 4 | 4 | 5 | 20 | 18 | |
| 6 | 2 | Montréal Impact | 22 | 8 | 6 | 8 | 35 | 37 | -2 | 30 | WWLL | 10 | 6 | 1 | 3 | 19 | 13 | 12 | 2 | 5 | 5 | 16 | 24 | |
| 7 | 1 | Orlando City | 24 | 8 | 6 | 10 | 25 | 36 | -11 | 30 | LLXL | 12 | 6 | 3 | 3 | 16 | 14 | 12 | 2 | 3 | 7 | 9 | 22 | |
| 8 | 1 | Philadelphia Union | 24 | 8 | 5 | 11 | 32 | 31 | +1 | 29 | LWLW | 13 | 7 | 2 | 4 | 23 | 17 | 11 | 1 | 3 | 7 | 9 | 14 | |
| 9 | New England Revolution | 23 | 8 | 5 | 10 | 38 | 38 | +0 | 29 | WLWW | 12 | 8 | 2 | 2 | 29 | 13 | 11 | 0 | 3 | 8 | 9 | 25 | ||
| 10 | D.C. United | 23 | 5 | 4 | 14 | 19 | 43 | -24 | 19 | XLLL | 11 | 3 | 3 | 5 | 8 | 15 | 12 | 2 | 1 | 9 | 11 | 28 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 1 | Houston Dynamo | 24 | 10 | 7 | 7 | 42 | 32 | +10 | 37 | WOXW | 12 | 9 | 3 | 0 | 33 | 11 | 12 | 1 | 4 | 7 | 9 | 21 | |
| 2 | 2 | Seattle Sounders | 24 | 10 | 7 | 7 | 37 | 31 | +6 | 37 | WWOW | 11 | 7 | 3 | 1 | 18 | 9 | 13 | 3 | 4 | 6 | 19 | 22 | |
| 3 | 2 | Sporting Kansas City | 24 | 9 | 10 | 5 | 29 | 19 | +10 | 37 | LXWX | 12 | 7 | 5 | 0 | 23 | 8 | 12 | 2 | 5 | 5 | 6 | 11 | |
| 4 | 1 | FC Dallas | 22 | 9 | 8 | 5 | 33 | 26 | +7 | 35 | OLLW | 12 | 6 | 4 | 2 | 21 | 14 | 10 | 3 | 4 | 3 | 12 | 12 | |
| 5 | 2 | Portland Timbers | 25 | 9 | 7 | 9 | 43 | 43 | +0 | 34 | LWXW | 12 | 6 | 4 | 2 | 25 | 16 | 13 | 3 | 3 | 7 | 18 | 27 | |
| 6 | 1 | San Jose Earthquakes | 24 | 9 | 5 | 10 | 26 | 38 | -12 | 32 | LWWL | 12 | 7 | 4 | 1 | 19 | 12 | 12 | 2 | 1 | 9 | 7 | 26 | |
| 7 | 1 | Vancouver Whitecaps | 22 | 9 | 4 | 9 | 32 | 32 | +0 | 31 | LXWL | 10 | 5 | 2 | 3 | 16 | 12 | 12 | 4 | 2 | 6 | 16 | 20 | |
| 8 | Real Salt Lake | 24 | 7 | 5 | 12 | 30 | 44 | -14 | 26 | OXXW | 12 | 4 | 4 | 4 | 12 | 13 | 12 | 3 | 1 | 8 | 18 | 31 | ||
| 9 | LA Galaxy | 23 | 6 | 5 | 12 | 32 | 42 | -10 | 23 | LLOL | 12 | 1 | 4 | 7 | 10 | 21 | 11 | 5 | 1 | 5 | 22 | 21 | ||
| 10 | 1 | Colorado Rapids | 22 | 6 | 4 | 12 | 22 | 31 | -9 | 22 | OXLX | 12 | 6 | 2 | 4 | 19 | 16 | 10 | 0 | 2 | 8 | 3 | 15 | |
| 11 | 1 | Minnesota United | 23 | 6 | 4 | 13 | 29 | 49 | -20 | 22 | LWLO | 14 | 6 | 2 | 6 | 19 | 23 | 9 | 0 | 2 | 7 | 10 | 26 | |
| 18 | +4 | David VILLA (New York City, 4p) |
| 16 | Nemanja NIKOLIĆ (Chicago Fire, 2p) | |
| 14 | +3 | Bradley WRIGHT-PHILLIPS (New York Red Bulls) |
| 13 | +2 | Diego VALERI (Portland Timbers, 3p) |
| 12 | Erick TORRES (Houston Dynamo, 5p) | |
| +1 | Ola KAMARA (Columbus Crew, 2p) | |
| C.J. SAPONG (Philadelphia Union, 3p) | ||
| David ACCAM (Chicago Fire, 2p) | ||
| 11 | Maximiliano URRUTI (FC Dallas, 1p) | |
| Sebastian GIOVINCO (Toronto FC, 1p) | ||
| Christian RAMIREZ (Minnesota United) | ||
| 10 | Fanendo ADI (Portland Timbers, 3p) | |
| +1 | Ignacio PIATTI (Montréal Impact, 4p) | |
| +1 | Clint DEMPSEY (Seattle Sounders, 1p) | |
| Daniel ROYER (New York Red Bulls, 3p) | ||
| Héctor VILLALBA (Atlanta United) | ||
| +1 | Justin MERAM (Columbus Crew) | |
| 9 | Chris WONDOLOWSKI (San Jose Earthquakes) | |
| Cyle LARIN (Orlando City) | ||
| Fredy MONTERO (Vancouver Whitecaps, 1p) | ||
| Federico HIGUAÍN (Columbus Crew, 2p) | ||
| Josef MARTÍNEZ (Atlanta United) | ||
| Jozy ALTIDORE (Toronto FC, 3p) |
| Sunday, 6 August 2017 | |||||
| Sporting Kansas City | 1-1 | Atlanta United | |||
| 59(p) | Feilhaber | 90 | Peterson | ||
| Portland Timbers | 3-1 | LA Galaxy | |||
| 5 | Ridgewell | 6 | Boateng | ||
| 33 | Valeri | ||||
| 53 | Powell | ||||
| New York City | 3-2 | New York Red Bulls | |||
| 28 | Villa | 41 | Wright-Phillips | ||
| 72 | Villa | 64 | Wright-Phillips | ||
| 75(p) | Villa | ||||
| Saturday, 12 August 2017 | |||||
| FC Dallas | 0-0 | Colorado Rapids | |||
| Houston Dynamo | 3-0 | San Jose Earthquakes | |||
| 21 | Elis | ||||
| 86 | Sánchez | ||||
| 90 | Manotas | ||||
| New York Red Bulls | 3-1 | Orlando City | |||
| 30(og) | Léo Pereira | 18 | Rivas | ||
| 60 | Wright-Phillips | ||||
| 80 | Davis | ||||
| Columbus Crew | 3-1 | Chicago Fire | |||
| 18 | Manneh | 13 | De Leeuw | ||
| 73 | Meram | ||||
| 88(p) | Kamara | ||||
| New England Revolution | 1-0 | Vancouver Whitecaps | |||
| 53 | Bunbury | ||||
| LA Galaxy | 0-2 | New York City | |||
| 54 | Lewis | ||||
| 73 | Villa | ||||
| Seattle Sounders | 1-0 | Sporting Kansas City | |||
| 36 | Dempsey | ||||
| Toronto FC | 4-1 | Portland Timbers | |||
| 58 | Morrow | 89 | Valeri | ||
| 72 | Víctor Vázquez | ||||
| 76 | Morrow | ||||
| 87 | Delgado | ||||
| Philadelphia Union | 0-3 | Montréal Impact | |||
| 69 | Džemaili | ||||
| 90 | Džemaili | ||||
| 90(p) | Piatti | ||||