| ROUND | R1 | QF | SF | F | ||||
| l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | |
| Season archive |
| Tuesday, 19 February 2019 | ||||||
| r1l1 |  Saprissa | 1-0 | Tigres | |||
| r1l1 |  Independiente | 4-0 | Toronto FC | |||
| r1l1 |  Guastatoya | 0-1 | Houston Dynamo | |||
| Wednesday, 20 February 2019 | ||||||
| r1l1 |  Marathón | 2-6 | Santos Laguna | |||
| r1l1 |  Alianza | 0-0 | Monterrey | |||
| r1l1 |  Pantoja | 0-2 | New York Red Bulls | |||
| Thursday, 21 February 2019 | ||||||
| r1l1 | Sporting Kansas City | 3-0 | Toluca | |||
| r1l1 | Herediano | 3-1 | Atlanta United | |||
| Tuesday, 26 February 2019 | ||||||
| r1l2 | Houston Dynamo | 2-1 | Guastatoya | 3-1 | ||
| r1l2 | Tigres | 5-1 | Saprissa | 5-2 | ||
| r1l2 | Toronto FC | 1-1 | Independiente | 1-5 | ||
| Wednesday, 27 February 2019 | ||||||
| r1l2 | New York Red Bulls | 3-0 | Pantoja | 5-0 | ||
| r1l2 | Monterrey | 1-0 | Alianza | 1-0 | ||
| r1l2 | Santos Laguna | 5-0 | Marathón | 11-2 | ||
| Thursday, 28 February 2019 | ||||||
| r1l2 | Toluca | 0-2 | Sporting Kansas City | 0-5 | ||
| r1l2 | Atlanta United | 4-0 | Herediano | 5-3 | ||
| 3 | +3 | Enner VALENCIA (Tigres, 1p) |
| +3 | Javier CORREA (Santos Laguna) | |
| 2 | +2 | Krisztián NÉMETH (Sporting Kansas City, 1p) |
| +2 | Julio FURCH (Santos Laguna) | |
| +2 | GERSO Fernandes (Sporting Kansas City) | |
| +2 | Julian GRESSEL (Atlanta United) | |
| +2 | Mauro MANOTAS (Houston Dynamo) | |
| +2 | Omar BROWNE (Independiente) | |
| +2 | Daniel ROYER (New York Red Bulls, 1p) | |
| +2 | Romeesh IVEY (Independiente) | |
| +2 | Josef MARTÍNEZ (Atlanta United) | |
| +2 | Marlos MORENO (Santos Laguna) |
