Primera A| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | Apertura |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | Finalización |
| Season archive |
| Games | Goals | H | D | A | ||||
| 171 | 374 | 2.18 | 72 | 42.11% | 58 | 33.92% | 41 | 23.98% |
| Apertura | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
 | 1 |  | Nacional | 18 | 10 | 4 | 4 | 37 | 15 | +22 | 34 | WLWL | 9 | 8 | 1 | 0 | 30 | 6 | 9 | 2 | 3 | 4 | 7 | 9 |
| 2 | | Santa Fé | 18 | 9 | 6 | 3 | 25 | 14 | +11 | 33 | WLWX | 9 | 5 | 3 | 1 | 14 | 7 | 9 | 4 | 3 | 2 | 11 | 7 |
| 3 |  4 | Millonarios | 18 | 10 | 3 | 5 | 25 | 18 | +7 | 33 | WWOL | 9 | 6 | 1 | 2 | 17 | 12 | 9 | 4 | 2 | 3 | 8 | 6 |
 | 4 | 2 | Cali | 18 | 8 | 7 | 3 | 19 | 14 | +5 | 31 | LWWX | 9 | 3 | 5 | 1 | 7 | 6 | 9 | 5 | 2 | 2 | 12 | 8 |
| 5 |  1 | Tolima | 18 | 8 | 6 | 4 | 22 | 14 | +8 | 30 | LOOW | 9 | 6 | 2 | 1 | 13 | 7 | 9 | 2 | 4 | 3 | 9 | 7 |
| 6 | 3 | La Equidad | 18 | 8 | 6 | 4 | 21 | 18 | +3 | 30 | LWLO | 9 | 5 | 2 | 2 | 12 | 10 | 9 | 3 | 4 | 2 | 9 | 8 |
| 7 | 2 | Junior | 18 | 8 | 5 | 5 | 21 | 13 | +8 | 29 | OOWX | 9 | 5 | 3 | 1 | 13 | 5 | 9 | 3 | 2 | 4 | 8 | 8 |
| 8 | | América | 18 | 7 | 8 | 3 | 19 | 12 | +7 | 29 | WOLW | 9 | 3 | 4 | 2 | 7 | 5 | 9 | 4 | 4 | 1 | 12 | 7 |
| 9 | | Medellín | 18 | 6 | 8 | 4 | 17 | 15 | +2 | 26 | LXLO | 9 | 3 | 6 | 0 | 10 | 7 | 9 | 3 | 2 | 4 | 7 | 8 | |
| 10 | | Jaguares | 18 | 7 | 4 | 7 | 21 | 21 | +0 | 25 | OOWL | 9 | 5 | 1 | 3 | 11 | 9 | 9 | 2 | 3 | 4 | 10 | 12 | |
| 11 | 1 | Bucaramanga | 18 | 6 | 6 | 6 | 20 | 16 | +4 | 24 | WXOL | 9 | 5 | 2 | 2 | 13 | 6 | 9 | 1 | 4 | 4 | 7 | 10 | |
| 12 | 1 | Deportivo Pasto | 18 | 4 | 11 | 3 | 19 | 20 | -1 | 23 | LXOO | 9 | 2 | 6 | 1 | 8 | 7 | 9 | 2 | 5 | 2 | 11 | 13 | |
| 13 | 2 | Chicó | 18 | 5 | 4 | 9 | 17 | 20 | -3 | 19 | OWOW | 9 | 4 | 2 | 3 | 10 | 6 | 9 | 1 | 2 | 6 | 7 | 14 | |
| 14 | 4 | Pereira | 18 | 4 | 6 | 8 | 16 | 24 | -8 | 18 | WWWX | 9 | 3 | 4 | 2 | 8 | 5 | 9 | 1 | 2 | 6 | 8 | 19 | |
| 15 | 2 | Once Caldas | 18 | 3 | 8 | 7 | 20 | 23 | -3 | 17 | WXLX | 9 | 3 | 2 | 4 | 12 | 10 | 9 | 0 | 6 | 3 | 8 | 13 | |
| 16 | 3 | Envigado | 18 | 3 | 8 | 7 | 15 | 23 | -8 | 17 | XLLW | 9 | 3 | 4 | 2 | 10 | 7 | 9 | 0 | 4 | 5 | 5 | 16 | |
| 17 | 3 | Patriotas | 18 | 5 | 2 | 11 | 17 | 31 | -14 | 17 | LXWL | 9 | 3 | 2 | 4 | 9 | 10 | 9 | 2 | 0 | 7 | 8 | 21 | |
| 18 | 2 | Rionegro | 18 | 2 | 8 | 8 | 13 | 24 | -11 | 14 | LLOX | 9 | 0 | 5 | 4 | 6 | 14 | 9 | 2 | 3 | 4 | 7 | 10 | |
| 19 | | Alianza Petrolera | 18 | 0 | 6 | 12 | 10 | 39 | -29 | 6 | XXLL | 9 | 0 | 3 | 6 | 5 | 20 | 9 | 0 | 3 | 6 | 5 | 19 | |
| Thursday, 15 April 2021 | ||||||
| 16 | Deportivo Pasto | 1-1 | Bucaramanga | |||
| Friday, 16 April 2021 | ||||||
| 19 | Alianza Petrolera | 1-1 | Envigado | |||
| Sunday, 18 April 2021 | ||||||
| 19 | Nacional | 7-1 | Patriotas | |||
| 19 | Millonarios | 3-1 | Cali | |||
| 19 | América | 2-0 | Tolima | |||
| 19 | Once Caldas | 2-0 | Medellín | |||
| 19 | Bucaramanga | 4-1 | Rionegro | |||
| 19 | Pereira | 4-2 | Deportivo Pasto | |||
| 19 | Chicó | 0-0 | Jaguares | |||
| 19 | La Equidad | 1-2 | Santa Fé | |||
| Cuadrangulares | ||||||
| Saturday, 24 April 2021 | ||||||
| qfl1 | América | - | Millonarios | |||
| qfl1 | Tolima | - | Cali | |||
| qfl1 | Junior | - | Santa Fé | |||
| qfl1 | La Equidad | - | Nacional | |||
| Saturday, 1 May 2021 | ||||||
| qfl2 | Nacional | - | La Equidad | |||
| qfl2 | Cali | - | Tolima | |||
| qfl2 | Millonarios | - | América | |||
| qfl2 | Santa Fé | - | Junior | |||
| 11 | +4 | Jefferson DUQUE (Nacional, 5p) |
| 9 | Diego HERAZO (La Equidad, 4p) | |
| 7 | Agustín VULETICH (Medellín, 2p) | |
| +1 | Cristian ARANGO (Millonarios, 2p) | |
| +1 | Fernando URIBE (Millonarios, 1p) | |
| 6 | David LEMOS (Once Caldas, 3p) | |
| Pablo ROJAS (Jaguares, 3p) | ||
| Miguel BORJA (Junior, 1p) | ||
| Brayan MORENO (Chicó) | ||
| Jesús ARRIETA (Patriotas) | ||
| Jarlan BARRERA (Nacional, 1p) | ||
| Kelvin OSORIO (Santa Fé) | ||
| 5 | +2 | Alejandro QUINTANA (Bucaramanga) |
| +1 | Ray VANEGAS (Deportivo Pasto) | |
| 4 | Santiago MORENO (América) | |
| Yesus CABRERA (América) | ||
| Yeison GUZMÁN (Envigado, 1p) | ||
| Marco PÉREZ (Cali, 2p) | ||
| +1 | Mender GARCÍA (Once Caldas) | |
| Sergio MOSQUERA (Tolima, 2p) | ||
| +1 | Gastón RODRÍGUEZ (Cali, 2p) | |
| Brayan FERNÁNDEZ (Bucaramanga) | ||
| Anderson PLATA (Tolima) |
