| ROUND | Q1 | Q2 | R1 | R2 | QF | SF | F | |||||
| r1 | r2 | r3 | r4 | r5 | r6 | |||||||
| Season archive |
| Monday, 13 September 2021 | ||||||
| r2 |  Esteghlal | 0-2 | Al-Hilal | |||
| 39 | Gomis | |||||
| 56 | Al-Dawsari | |||||
| Tuesday, 14 September 2021 | ||||||
| r2 |  Nagoya Grampus 8 | 4-2 | Daegu FC | |||
| 12 | Świerczok | 4 | Cesinha | |||
| 63 | Świerczok | 28 | Edgar Silva | |||
| 65 | Świerczok | |||||
| 79 | Nakatani | |||||
| r2 | Ulsan Hyundai | 0-0 | Kawasaki Frontale | aet, p3-2 | ||
| r2 | Al-Nassr | 1-0 | Teraktor Sazi | |||
| 11 | Aboubakar | |||||
| r2 |  Sharjah | 1-1 | Al-Wahda | aet, p4-5 | ||
| 58 | Bernard | 56 | Kharbin | |||
| r2 |  Istiklol | 0-1 | Perspolis | |||
| 90 | Torabi | |||||
| Wednesday, 15 September 2021 | ||||||
| r2 | Cerezo Osaka | 0-1 | Pohang Steelers | |||
| 25 | Lee | |||||
| r2 | Chonbuk Motors | 1-1 | BG Pathum United | aet, p4-2 | ||
| 45 | Gustavo | 76 | Dangda | |||
| 8 | +1 | GUSTAVO Henrique (Chonbuk Motors, 3p) |
| Michael OLUNGA (Al-Duhail, 1p) | ||
| 6 | Anderson PATRIC (Gamba Osaka) | |
| LEANDRO DAMIÃO da Silva (Kawasaki Frontale) | ||
| +1 | EDGAR Bruno SILVA (Daegu FC) | |
| Modou BARROW (Chonbuk Motors) | ||
| 5 | +1 | CESINHA (Daegu FC) |
| Cheick DIABATÉ (Esteghlal, 3p) | ||
| 4 | Kento TACHIBANADA (Kawasaki Frontale) | |
| MATEUS dos Santos (Nagoya Grampus 8, 2p) | ||
| Stanislav ILJUTCENKO (Chonbuk Motors) | ||
| Shahriar MOGHANLOU (Perspolis) | ||
| Ryogo YAMASAKI (Nagoya Grampus 8) | ||
| Mohammad ABBASZADEH (Teraktor Sazi, 1p) | ||
| Zafar POLVONOV (AGMK) | ||
| Abderrazak HAMDALLAH (Al-Nassr, 2p) | ||
| +1 | Bafétimbi GOMIS (Al-Hilal) | |
| Omar AL-SOMAH (Al-Ahli, 1p) | ||
| KEI Chinen (Kawasaki Frontale, 1p) | ||
| Dejan DAMJANOVIĆ (Kitchee, 2p) |
