MLS is Back| ROUND | G | R2 | QF | SF | F | ||
| r1 | r2 | r3 | |||||
| Group A | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Orlando City | 1 | 1 | 0 | 0 | 2 | 1 | +1 | 3 | W--- | ||
| 2 | Philadelphia Union | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W--- | ||
| 3 | Inter Miami | 1 | 0 | 0 | 1 | 1 | 2 | -1 | 0 | L--- | ||
| 4 | New York City | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L--- | ||
| Wednesday, 8 July 2020 | |||||
| 1 | Orlando City | 2-1 | Inter Miami | ||
| 70 | Mueller | 47 | Agudelo | ||
| 90 | Nani | ||||
| Thursday, 9 July 2020 | |||||
| 1 | New York City | 0-1 | Philadelphia Union | ||
| 63 | Bedoya | ||||
| Group B | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Vancouver Whitecaps | 1 | 1 | 0 | 0 | 2 | 0 | +2 | 3 | W--- | ||
| 2 | San Jose Earthquakes | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | O--- | ||
| 3 | Seattle Sounders | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | O--- | ||
| 4 | Chicago Fire | 1 | 0 | 0 | 1 | 0 | 2 | -2 | 0 | L--- | ||
| Friday, 10 July 2020 | |||||
| 1 | Seattle Sounders | 0-0 | San Jose Earthquakes | ||
| Thursday, 23 July 2020 | |||||
| 1 | Chicago Fire | 0-2 | Vancouver Whitecaps | ||
| 65 | Reyna | ||||
| 71 | Dájome | ||||
| Group C | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | New England Revolution | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W--- | ||
| 2 | Toronto FC | 1 | 0 | 1 | 0 | 2 | 2 | +0 | 1 | X--- | ||
| 3 | D.C. United | 1 | 0 | 1 | 0 | 2 | 2 | +0 | 1 | X--- | ||
| 4 | Montréal Impact | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L--- | ||
| Thursday, 9 July 2020 | |||||
| 1 | Montréal Impact | 0-1 | New England Revolution | ||
| 56 | Bou | ||||
| Monday, 13 July 2020 | |||||
| 1 | Toronto FC | 2-2 | D.C. United | ||
| 12 | Akinola | 84 | Higuaín | ||
| 44 | Akinola | 90 | Brillant | ||
| Group D | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Real Salt Lake | 1 | 1 | 0 | 0 | 2 | 0 | +2 | 3 | W--- | ||
| 2 | Minnesota United | 1 | 1 | 0 | 0 | 2 | 1 | +1 | 3 | W--- | ||
| 3 | Sporting Kansas City | 1 | 0 | 0 | 1 | 1 | 2 | -1 | 0 | L--- | ||
| 4 | Colorado Rapids | 1 | 0 | 0 | 1 | 0 | 2 | -2 | 0 | L--- | ||
| Sunday, 12 July 2020 | |||||
| 1 | Sporting Kansas City | 1-2 | Minnesota United | ||
| 43 | Shelton | 90(og) | Shelton | ||
| 90 | Molino | ||||
| 1 | Real Salt Lake | 2-0 | Colorado Rapids | ||
| 27 | Rusnák | ||||
| 76 | Kreilach | ||||
| Group E | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Columbus Crew | 1 | 1 | 0 | 0 | 4 | 0 | +4 | 3 | W--- | ||
| 2 | New York | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W--- | ||
| 3 | Atlanta United | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L--- | ||
| 4 | FC Cincinnati | 1 | 0 | 0 | 1 | 0 | 4 | -4 | 0 | L--- | ||
| Saturday, 11 July 2020 | |||||
| 1 | Atlanta United | 0-1 | New York | ||
| 4 | Valot | ||||
| 1 | FC Cincinnati | 0-4 | Columbus Crew | ||
| 27 | Zelarayán | ||||
| 30 | Zardes | ||||
| 49 | Zardes | ||||
| 60 | Mokhtar | ||||
| Group F | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Portland Timbers | 1 | 1 | 0 | 0 | 2 | 1 | +1 | 3 | W--- | ||
| 2 | Houston Dynamo | 1 | 0 | 1 | 0 | 3 | 3 | +0 | 1 | X--- | ||
| 3 | Los Angeles | 1 | 0 | 1 | 0 | 3 | 3 | +0 | 1 | X--- | ||
| 4 | LA Galaxy | 1 | 0 | 0 | 1 | 1 | 2 | -1 | 0 | L--- | ||
| Monday, 13 July 2020 | |||||
| 1 | LA Galaxy | 1-2 | Portland Timbers | ||
| 87 | Hernández | 59 | Ebobisse | ||
| 66 | Blanco | ||||
| 1 | Los Angeles | 3-3 | Houston Dynamo | ||
| 19 | Wright-Phillips | 9 | Rodriguez | ||
| 63 | Rossi | 30 | Rodriguez | ||
| 69 | Rodríguez | 45 | Elis | ||
| 2 | +2 | Memo RODRIGUEZ (Houston Dynamo) |
| +2 | Gyasi ZARDES (Columbus Crew) | |
| +2 | Ayo AKINOLA (Toronto FC) | |
| 1 | +1 | Chris MUELLER (Orlando City) |
| +1 | Yordy REYNA () | |
| +1 | Jeremy EBOBISSE (Portland Timbers) | |
| +1 | Cristian DÁJOME () | |
| +1 | Javier HERNÁNDEZ (LA Galaxy) | |
| +1 | Lucas ZELARAYÁN (Columbus Crew) | |
| +1 | Albert RUSNÁK (Real Salt Lake) | |
| +1 | Frédéric BRILLANT (D.C. United) | |
| +1 | Alejandro BEDOYA (Philadelphia Union) | |
| +1 | NANI (Orlando City) | |
| +1 | Gustavo BOU (New England Revolution) | |
| +1 | Diego ROSSI (Los Angeles) | |
| +1 | Khiry SHELTON (Sporting Kansas City) | |
| +1 | Juan AGUDELO (Inter Miami) | |
| +1 | Bradley WRIGHT-PHILLIPS (Los Angeles) | |
| +1 | Kevin MOLINO (Minnesota United) | |
| +1 | Florian VALOT (New York) | |
| +1 | Alberth ELIS (Houston Dynamo) | |
| +1 | Youness MOKHTAR (Columbus Crew) | |
| +1 | Federico HIGUAÍN (D.C. United) | |
| +1 | Damir KREILACH (Real Salt Lake) | |
| +1 | Brian RODRÍGUEZ (Los Angeles) | |
| +1 | Sebastian BLANCO (Portland Timbers) |
