Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 242 | 650 | 2.68 | 129 | 53.31% | 50 | 20.66% | 63 | 26.03% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Sporting Kansas City | 25 | 14 | 4 | 7 | 31 | 22 | +9 | 46 | WWWL | 12 | 7 | 2 | 3 | 14 | 8 | 13 | 7 | 2 | 4 | 17 | 14 | ||
| 2 | New York Red Bulls | 25 | 13 | 5 | 7 | 43 | 36 | +7 | 44 | WWLL | 12 | 9 | 3 | 0 | 27 | 12 | 13 | 4 | 2 | 7 | 16 | 24 | ||
| 3 | 1 | Houston Dynamo | 26 | 11 | 9 | 6 | 38 | 30 | +8 | 42 | XXLW | 13 | 8 | 5 | 0 | 24 | 10 | 13 | 3 | 4 | 6 | 14 | 20 | |
| 4 | 1 | Chicago Fire | 25 | 12 | 5 | 8 | 32 | 30 | +2 | 41 | LWWW | 12 | 8 | 2 | 2 | 17 | 11 | 13 | 4 | 3 | 6 | 15 | 19 | |
| 5 | D.C. United | 25 | 12 | 4 | 9 | 41 | 35 | +6 | 40 | LWXL | 13 | 9 | 3 | 1 | 29 | 12 | 12 | 3 | 1 | 8 | 12 | 23 | ||
| 6 | Montréal Impact | 28 | 12 | 3 | 13 | 42 | 44 | -2 | 39 | WWWW | 15 | 10 | 2 | 3 | 31 | 18 | 13 | 2 | 1 | 10 | 11 | 26 | ||
| 7 | Columbus Crew | 24 | 10 | 6 | 8 | 29 | 28 | +1 | 36 | WWXX | 12 | 7 | 2 | 3 | 19 | 16 | 12 | 3 | 4 | 5 | 10 | 12 | ||
| 8 | 1 | Philadelphia Union | 23 | 7 | 4 | 12 | 24 | 28 | -4 | 25 | OXLL | 12 | 5 | 2 | 5 | 17 | 13 | 11 | 2 | 2 | 7 | 7 | 15 | |
| 9 | 1 | New England Revolution | 25 | 6 | 5 | 14 | 30 | 35 | -5 | 23 | LLLL | 12 | 5 | 3 | 4 | 16 | 11 | 13 | 1 | 2 | 10 | 14 | 24 | |
| 10 | Toronto FC | 26 | 5 | 6 | 15 | 29 | 46 | -17 | 21 | XLLX | 13 | 3 | 3 | 7 | 13 | 21 | 13 | 2 | 3 | 8 | 16 | 25 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | San Jose Earthquakes | 26 | 15 | 5 | 6 | 52 | 33 | +19 | 50 | WLWX | 13 | 9 | 3 | 1 | 32 | 15 | 13 | 6 | 2 | 5 | 20 | 18 | ||
| 2 | 1 | Seattle Sounders | 25 | 12 | 7 | 6 | 40 | 26 | +14 | 43 | WWLW | 12 | 8 | 1 | 3 | 18 | 7 | 13 | 4 | 6 | 3 | 22 | 19 | |
| 3 | 1 | Real Salt Lake | 27 | 13 | 4 | 10 | 37 | 32 | +5 | 43 | OLLL | 14 | 9 | 1 | 4 | 24 | 14 | 13 | 4 | 3 | 6 | 13 | 18 | |
| 4 | LA Galaxy | 26 | 11 | 4 | 11 | 44 | 40 | +4 | 37 | XWLW | 11 | 5 | 1 | 5 | 19 | 16 | 15 | 6 | 3 | 6 | 25 | 24 | ||
| 5 | Vancouver Whitecaps | 27 | 10 | 7 | 10 | 29 | 35 | -6 | 37 | LLLW | 13 | 7 | 4 | 2 | 19 | 14 | 14 | 3 | 3 | 8 | 10 | 21 | ||
| 6 | FC Dallas | 27 | 8 | 8 | 11 | 33 | 35 | -2 | 32 | WWWX | 14 | 5 | 6 | 3 | 17 | 13 | 13 | 3 | 2 | 8 | 16 | 22 | ||
| 7 | Chivas USA | 23 | 7 | 6 | 10 | 17 | 32 | -15 | 27 | LXLW | 13 | 3 | 2 | 8 | 8 | 21 | 10 | 4 | 4 | 2 | 9 | 11 | ||
| 8 | Colorado Rapids | 26 | 8 | 2 | 16 | 33 | 40 | -7 | 26 | LXLW | 13 | 6 | 2 | 5 | 22 | 14 | 13 | 2 | 0 | 11 | 11 | 26 | ||
| 9 | Portland Timbers | 25 | 6 | 6 | 13 | 26 | 43 | -17 | 24 | WLXX | 13 | 6 | 3 | 4 | 20 | 18 | 12 | 0 | 3 | 9 | 6 | 25 | ||
| 18 | Chris WONDOLOWSKI (San Jose Earthquakes) | |
| 14 | +1 | Kenny COOPER (New York Red Bulls) |
| Álvaro SABORIO (Real Salt Lake) | ||
| 11 | Eddie JOHNSON (Seattle Sounders) | |
| Robbie KEANE (LA Galaxy) | ||
| +3 | Fredy MONTERO (Seattle Sounders) | |
| +1 | Will BRUIN (Houston Dynamo) | |
| +2 | Alan GORDON (San Jose Earthquakes) | |
| Thierry HENRY (New York Red Bulls) | ||
| 10 | Chris PONTIUS (D.C. United) | |
| 9 | Landon DONOVAN (LA Galaxy) | |
| Kei KAMARA (Sporting Kansas City) | ||
| Danny KOEVERMANS (Toronto FC) | ||
| Saër SÈNE (New England Revolution) | ||
| +2 | Patrice BERNIER (Montréal Impact) | |
| 8 | Steven LENHART (San Jose Earthquakes) | |
| 7 | Darren MATTOCKS (Vancouver Whitecaps) | |
| Kris BOYD (Portland Timbers) | ||
| MAICON CARIOCA (D.C. United) | ||
| 6 | +2 | Simon DAWKINS (San Jose Earthquakes) |
| +1 | Brad DAVIS (Houston Dynamo) | |
| +2 | Darlington NAGBE (Portland Timbers) | |
| +1 | Lionard PAJOY (D.C. United) | |
| +2 | Eddie GAVEN (Columbus Crew) | |
| Jaime CASTRILLÓN (Colorado Rapids) | ||
| Edgar ESPÍNDOLA (Real Salt Lake) | ||
| +1 | Dwayne DE ROSARIO (D.C. United) | |
| Marco PAPPA (Chicago Fire) | ||
| David BECKHAM (LA Galaxy) |
| Sunday, 19 August 2012 | |||||
| D.C. United | 1-1 | Philadelphia Union | |||
| 71(og) | Okugo | 8 | Carroll | ||
| New York Red Bulls | 3-2 | Portland Timbers | |||
| 42 | Cooper | 8 | Dike | ||
| 45 | Cahill | 32 | Nagbe | ||
| 83 | Pearce | ||||
| Houston Dynamo | 2-2 | Columbus Crew | |||
| 19 | Davis | 33 | Grossman | ||
| 82 | Moffat | 58 | Gaven | ||
| Wednesday, 22 August 2012 | |||||
| D.C. United | 4-2 | Chicago Fire | |||
| 19 | De Rosario | 44 | Paladini | ||
| 46 | Pajoy | 75 | Segares | ||
| 51 | McDonald | ||||
| 89 | Tan | ||||
| Columbus Crew | 2-1 | Toronto FC | |||
| 4 | Gaven | 71 | Silva | ||
| 58 | Higuaín | ||||
| Friday, 24 August 2012 | |||||
| Philadelphia Union | 0-0 | Real Salt Lake | |||
| Saturday, 25 August 2012 | |||||
| Houston Dynamo | 1-1 | Toronto FC | |||
| 21 | Bruin | 85 | Dunfield | ||
| Montréal Impact | 3-0 | D.C. United | |||
| 24 | Di Vaio | ||||
| 50 | Bernier | ||||
| 90 | Bernier | ||||
| Portland Timbers | 2-1 | Vancouver Whitecaps | |||
| 41 | Nagbe | 46 | Miller | ||
| 55 | Songo'o | ||||
| Chivas USA | 2-6 | Seattle Sounders | |||
| 38 | Agudelo | 10 | Evans | ||
| 64 | Bolaños | 27 | Montero | ||
| 34 | Montero | ||||
| 67 | Montero | ||||
| 80 | Ochoa | ||||
| 90(og) | Jazic | ||||
| San Jose Earthquakes | 4-1 | Colorado Rapids | |||
| 11 | Dawkins | 54 | Marshall | ||
| 43 | Gordon | ||||
| 68 | Dawkins | ||||
| 75 | Gordon | ||||
| Columbus Crew | 4-3 | New England Revolution | |||
| 26 | Higuaín | 17 | Guy | ||
| 32 | Arrieta | 23 | Bengtson | ||
| 43 | Higuaín | 81 | Nguyen | ||
| 86 | Arrieta | ||||
