Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 300 | 805 | 2.68 | 158 | 52.67% | 67 | 22.33% | 75 | 25.00% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Sporting Kansas City | 31 | 17 | 7 | 7 | 39 | 25 | +14 | 58 | WOWX | 16 | 9 | 4 | 3 | 20 | 11 | 15 | 8 | 3 | 4 | 19 | 14 | ||
| 2 | 1 | Chicago Fire | 32 | 17 | 5 | 10 | 45 | 39 | +6 | 56 | WLLW | 16 | 11 | 2 | 3 | 26 | 17 | 16 | 6 | 3 | 7 | 19 | 22 | |
| 3 | 1 | D.C. United | 32 | 16 | 6 | 10 | 49 | 40 | +9 | 54 | WXWW | 16 | 11 | 4 | 1 | 34 | 15 | 16 | 5 | 2 | 9 | 15 | 25 | |
| 4 | 2 | New York Red Bulls | 32 | 15 | 8 | 9 | 54 | 46 | +8 | 53 | LWXL | 16 | 11 | 3 | 2 | 34 | 18 | 16 | 4 | 5 | 7 | 20 | 28 | |
| 5 | Houston Dynamo | 32 | 13 | 11 | 8 | 45 | 38 | +7 | 50 | XWLX | 16 | 10 | 6 | 0 | 28 | 11 | 16 | 3 | 5 | 8 | 17 | 27 | ||
| 6 | Columbus Crew | 31 | 14 | 6 | 11 | 39 | 39 | +0 | 48 | WLWL | 15 | 10 | 2 | 3 | 25 | 19 | 16 | 4 | 4 | 8 | 14 | 20 | ||
| 7 | Montréal Impact | 32 | 12 | 5 | 15 | 45 | 50 | -5 | 41 | XOLL | 16 | 10 | 3 | 3 | 31 | 18 | 16 | 2 | 2 | 12 | 14 | 32 | ||
| 8 | Philadelphia Union | 31 | 10 | 6 | 15 | 35 | 37 | -2 | 36 | WWLW | 16 | 7 | 2 | 7 | 22 | 17 | 15 | 3 | 4 | 8 | 13 | 20 | ||
| 9 | New England Revolution | 32 | 7 | 8 | 17 | 37 | 44 | -7 | 29 | LLXL | 16 | 6 | 6 | 4 | 22 | 15 | 16 | 1 | 2 | 13 | 15 | 29 | ||
| 10 | Toronto FC | 32 | 5 | 7 | 20 | 35 | 60 | -25 | 22 | LLLX | 16 | 3 | 4 | 9 | 15 | 25 | 16 | 2 | 3 | 11 | 20 | 35 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | San Jose Earthquakes | 32 | 19 | 7 | 6 | 69 | 40 | +29 | 64 | WXWX | 16 | 10 | 5 | 1 | 41 | 20 | 16 | 9 | 2 | 5 | 28 | 20 | ||
| 2 | Real Salt Lake | 32 | 17 | 4 | 11 | 46 | 35 | +11 | 55 | WWWL | 16 | 11 | 1 | 4 | 27 | 15 | 16 | 6 | 3 | 7 | 19 | 20 | ||
| 3 | 1 | LA Galaxy | 32 | 15 | 5 | 12 | 56 | 45 | +11 | 50 | LXWW | 16 | 9 | 1 | 6 | 30 | 20 | 16 | 6 | 4 | 6 | 26 | 25 | |
| 4 | 1 | Seattle Sounders | 30 | 13 | 10 | 7 | 45 | 31 | +14 | 49 | OLXW | 14 | 9 | 1 | 4 | 21 | 10 | 16 | 4 | 9 | 3 | 24 | 21 | |
| 5 | Vancouver Whitecaps | 32 | 11 | 9 | 12 | 35 | 40 | -5 | 42 | WOXL | 16 | 8 | 6 | 2 | 25 | 16 | 16 | 3 | 3 | 10 | 10 | 24 | ||
| 6 | FC Dallas | 31 | 9 | 10 | 12 | 38 | 41 | -3 | 37 | XWXL | 16 | 6 | 7 | 3 | 19 | 14 | 15 | 3 | 3 | 9 | 19 | 27 | ||
| 7 | Colorado Rapids | 32 | 9 | 4 | 19 | 40 | 50 | -10 | 31 | LXXL | 16 | 7 | 3 | 6 | 27 | 19 | 16 | 2 | 1 | 13 | 13 | 31 | ||
| 8 | Portland Timbers | 31 | 7 | 9 | 15 | 32 | 52 | -20 | 30 | XLXX | 16 | 7 | 5 | 4 | 23 | 20 | 15 | 0 | 4 | 11 | 9 | 32 | ||
| 9 | Chivas USA | 31 | 7 | 7 | 17 | 21 | 53 | -32 | 28 | LLLL | 15 | 3 | 2 | 10 | 8 | 27 | 16 | 4 | 5 | 7 | 13 | 26 | ||
| 25 | +3 | Chris WONDOLOWSKI (San Jose Earthquakes) |
| 17 | Álvaro SABORIO (Real Salt Lake) | |
| 16 | Kenny COOPER (New York Red Bulls) | |
| 15 | +1 | Robbie KEANE (LA Galaxy) |
| 14 | Thierry HENRY (New York Red Bulls) | |
| 13 | Eddie JOHNSON (Seattle Sounders) | |
| Alan GORDON (San Jose Earthquakes) | ||
| 12 | Chris PONTIUS (D.C. United) | |
| Fredy MONTERO (Seattle Sounders) | ||
| +1 | Will BRUIN (Houston Dynamo) | |
| 11 | Kei KAMARA (Sporting Kansas City) | |
| Saër SÈNE (New England Revolution) | ||
| 10 | Steven LENHART (San Jose Earthquakes) | |
| 9 | Landon DONOVAN (LA Galaxy) | |
| +2 | Edgar ESPÍNDOLA (Real Salt Lake) | |
| Danny KOEVERMANS (Toronto FC) | ||
| Patrice BERNIER (Montréal Impact) | ||
| 8 | Simon DAWKINS (San Jose Earthquakes) | |
| Chris ROLFE (Chicago Fire) | ||
| +1 | Jaime CASTRILLÓN (Colorado Rapids) | |
| Jairo ARRIETA (Columbus Crew) |
| Sunday, 30 September 2012 | |||||
| Colorado Rapids | 1-1 | LA Galaxy | |||
| 16 | Castrillón | 10 | Marcelo | ||
| Wednesday, 3 October 2012 | |||||
| Chicago Fire | 1-3 | Philadelphia Union | |||
| 69 | Oduro | 7 | McInerney | ||
| 67 | Gómez | ||||
| 87 | Hoppenot | ||||
| Vancouver Whitecaps | 4-0 | Chivas USA | |||
| 11 | Koffie | ||||
| 35 | Richards | ||||
| 62 | Camilo | ||||
| 73 | Robson | ||||
| Saturday, 6 October 2012 | |||||
| Houston Dynamo | 1-1 | Montréal Impact | |||
| 44 | Bruin | 66 | Nyassi | ||
| New York Red Bulls | 0-2 | Chicago Fire | |||
| 65 | Macdonald | ||||
| 78 | Macdonald | ||||
| Toronto FC | 0-1 | D.C. United | |||
| 88 | Salihi | ||||
| Philadelphia Union | 1-0 | New England Revolution | |||
| 73 | McInerney | ||||
| Colorado Rapids | 1-4 | San Jose Earthquakes | |||
| 90 | Akpan | 2 | Chávez | ||
| 11 | Wondolowski | ||||
| 51 | Wondolowski | ||||
| 83 | Wondolowski | ||||
| LA Galaxy | 1-2 | Real Salt Lake | |||
| 17 | Keane | 25 | Espíndola | ||
| 28 | Espíndola | ||||
