Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 310 | 824 | 2.65 | 162 | 52.26% | 72 | 23.23% | 76 | 24.52% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Sporting Kansas City | 33 | 17 | 9 | 7 | 40 | 26 | +14 | 60 | OXWO | 16 | 9 | 4 | 3 | 20 | 11 | 17 | 8 | 5 | 4 | 20 | 15 | ||
| 2 | 1 | D.C. United | 33 | 17 | 6 | 10 | 52 | 42 | +10 | 57 | WWXW | 17 | 12 | 4 | 1 | 37 | 17 | 16 | 5 | 2 | 9 | 15 | 25 | |
| 3 | 1 | Chicago Fire | 33 | 17 | 5 | 11 | 45 | 40 | +5 | 56 | LWLL | 16 | 11 | 2 | 3 | 26 | 17 | 17 | 6 | 3 | 8 | 19 | 23 | |
| 4 | New York Red Bulls | 33 | 15 | 9 | 9 | 54 | 46 | +8 | 54 | OLWX | 17 | 11 | 4 | 2 | 34 | 18 | 16 | 4 | 5 | 7 | 20 | 28 | ||
| 5 | Houston Dynamo | 33 | 14 | 11 | 8 | 48 | 39 | +9 | 53 | WXWL | 17 | 11 | 6 | 0 | 31 | 12 | 16 | 3 | 5 | 8 | 17 | 27 | ||
| 6 | Columbus Crew | 33 | 14 | 7 | 12 | 42 | 43 | -1 | 49 | LXWL | 16 | 10 | 3 | 3 | 26 | 20 | 17 | 4 | 4 | 9 | 16 | 23 | ||
| 7 | Montréal Impact | 33 | 12 | 6 | 15 | 45 | 50 | -5 | 42 | OXOL | 16 | 10 | 3 | 3 | 31 | 18 | 17 | 2 | 3 | 12 | 14 | 32 | ||
| 8 | Philadelphia Union | 32 | 10 | 6 | 16 | 36 | 40 | -4 | 36 | LWWL | 16 | 7 | 2 | 7 | 22 | 17 | 16 | 3 | 4 | 9 | 14 | 23 | ||
| 9 | New England Revolution | 33 | 8 | 8 | 17 | 38 | 44 | -6 | 32 | WLLX | 17 | 7 | 6 | 4 | 23 | 15 | 16 | 1 | 2 | 13 | 15 | 29 | ||
| 10 | Toronto FC | 33 | 5 | 8 | 20 | 35 | 60 | -25 | 23 | OLLL | 17 | 3 | 5 | 9 | 15 | 25 | 16 | 2 | 3 | 11 | 20 | 35 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | San Jose Earthquakes | 32 | 19 | 7 | 6 | 69 | 40 | +29 | 64 | WXWX | 16 | 10 | 5 | 1 | 41 | 20 | 16 | 9 | 2 | 5 | 28 | 20 | ||
| 2 | Real Salt Lake | 33 | 17 | 5 | 11 | 46 | 35 | +11 | 56 | OWWW | 16 | 11 | 1 | 4 | 27 | 15 | 17 | 6 | 4 | 7 | 19 | 20 | ||
| 3 | 1 | Seattle Sounders | 32 | 14 | 11 | 7 | 48 | 31 | +17 | 53 | OWOL | 16 | 10 | 2 | 4 | 24 | 10 | 16 | 4 | 9 | 3 | 24 | 21 | |
| 4 | 1 | LA Galaxy | 32 | 15 | 5 | 12 | 56 | 45 | +11 | 50 | LXWW | 16 | 9 | 1 | 6 | 30 | 20 | 16 | 6 | 4 | 6 | 26 | 25 | |
| 5 | Vancouver Whitecaps | 32 | 11 | 9 | 12 | 35 | 40 | -5 | 42 | WOXL | 16 | 8 | 6 | 2 | 25 | 16 | 16 | 3 | 3 | 10 | 10 | 24 | ||
| 6 | FC Dallas | 32 | 9 | 11 | 12 | 39 | 42 | -3 | 38 | XXWX | 16 | 6 | 7 | 3 | 19 | 14 | 16 | 3 | 4 | 9 | 20 | 28 | ||
| 7 | Colorado Rapids | 33 | 10 | 4 | 19 | 42 | 50 | -8 | 34 | WLXX | 16 | 7 | 3 | 6 | 27 | 19 | 17 | 3 | 1 | 13 | 15 | 31 | ||
| 8 | Portland Timbers | 32 | 7 | 9 | 16 | 32 | 55 | -23 | 30 | LXLX | 16 | 7 | 5 | 4 | 23 | 20 | 16 | 0 | 4 | 12 | 9 | 35 | ||
| 9 | Chivas USA | 33 | 7 | 8 | 18 | 22 | 56 | -34 | 29 | LXLL | 17 | 3 | 3 | 11 | 9 | 30 | 16 | 4 | 5 | 7 | 13 | 26 | ||
| 25 | Chris WONDOLOWSKI (San Jose Earthquakes) | |
| 17 | Álvaro SABORIO (Real Salt Lake) | |
| 16 | Kenny COOPER (New York Red Bulls) | |
| 15 | Robbie KEANE (LA Galaxy) | |
| 14 | +1 | Eddie JOHNSON (Seattle Sounders) |
| Thierry HENRY (New York Red Bulls) | ||
| 13 | +1 | Fredy MONTERO (Seattle Sounders) |
| Alan GORDON (San Jose Earthquakes) | ||
| 12 | Chris PONTIUS (D.C. United) | |
| Will BRUIN (Houston Dynamo) | ||
| 11 | Kei KAMARA (Sporting Kansas City) | |
| Saër SÈNE (New England Revolution) | ||
| 10 | Steven LENHART (San Jose Earthquakes) | |
| 9 | Landon DONOVAN (LA Galaxy) | |
| +2 | Eddie GAVEN (Columbus Crew) | |
| Edgar ESPÍNDOLA (Real Salt Lake) | ||
| +1 | Jairo ARRIETA (Columbus Crew) | |
| Danny KOEVERMANS (Toronto FC) | ||
| Patrice BERNIER (Montréal Impact) | ||
| 8 | Simon DAWKINS (San Jose Earthquakes) | |
| +1 | Blas PÉREZ (FC Dallas) | |
| Chris ROLFE (Chicago Fire) | ||
| +1 | Brad DAVIS (Houston Dynamo) | |
| Jaime CASTRILLÓN (Colorado Rapids) | ||
| +1 | Jack McINERNEY (Philadelphia Union) | |
| +1 | C.J. SAPONG (Sporting Kansas City) |
| Sunday, 7 October 2012 | |||||
| Columbus Crew | 1-1 | Sporting Kansas City | |||
| 90 | Gaven | 10 | Sapong | ||
| Chivas USA | 1-1 | FC Dallas | |||
| 69 | Villafaña | 8 | Pérez | ||
| Seattle Sounders | 3-0 | Portland Timbers | |||
| 25(og) | Danso | ||||
| 28 | Johnson | ||||
| 62 | Montero | ||||
| Wednesday, 17 October 2012 | |||||
| Seattle Sounders | 0-0 | Real Salt Lake | |||
| Saturday, 20 October 2012 | |||||
| Toronto FC | 0-0 | Montréal Impact | |||
| New York Red Bulls | 0-0 | Sporting Kansas City | |||
| Houston Dynamo | 3-1 | Philadelphia Union | |||
| 5 | Kandji | 19 | McInerney | ||
| 71 | García | ||||
| 75 | Davis | ||||
| New England Revolution | 1-0 | Chicago Fire | |||
| 17 | Fagúndez | ||||
| D.C. United | 3-2 | Columbus Crew | |||
| 39 | Deleon | 7 | Gaven | ||
| 59 | Gallo | 41 | Arrieta | ||
| 90 | Neal | ||||
| Chivas USA | 0-2 | Colorado Rapids | |||
| 16 | Rivero | ||||
| 43 | Hill | ||||
