| ROUND | R1 | R2 |
| Season archive |
| Group A | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Guaraní | 2 | 1 | 1 | 0 | 5 | 3 | +2 | 4 | WX-- | ||
| 2 | Nacional Potosí | 2 | 1 | 0 | 1 | 2 | 2 | +0 | 3 | LW-- | ||
| 3 | Independiente | 2 | 1 | 0 | 1 | 2 | 3 | -1 | 3 | WL-- | ||
| 4 | Boston River | 2 | 0 | 1 | 1 | 4 | 5 | -1 | 1 | LX-- | ||
| Tuesday, 1 April 2025 | |||||
| g |  Boston River | 3-3 | Guaraní | ||
| 27 | González | 54 | Mendieta | ||
| 50 | Noguera | 59 | Fernández | ||
| 72 | Albarracín | 90+1 | Vargas | ||
| g |  Nacional Potosí | 2-0 | Independiente | ||
| 66 | Ábrego | ||||
| 83 | Diellos | ||||
| Tuesday, 8 April 2025 | |||||
| g | Independiente | 2-1 | Boston River | ||
| 61 | Galdames | 86 | Muñoa | ||
| 90+1 | Galdames | ||||
| Thursday, 10 April 2025 | |||||
| g | Guaraní | 2-0 | Nacional Potosí | ||
| 11 | Fernández | ||||
| 45+5 | Patiño | ||||
| Tuesday, 22 April 2025 | |||||
| g | Guaraní | - | Independiente | ||
| g | Boston River | - | Nacional Potosí | ||
| Tuesday, 6 May 2025 | |||||
| g | Boston River | - | Independiente | ||
| g | Nacional Potosí | - | Guaraní | ||
| Tuesday, 13 May 2025 | |||||
| g | Nacional Potosí | - | Boston River | ||
| Thursday, 15 May 2025 | |||||
| g | Independiente | - | Guaraní | ||
| Wednesday, 28 May 2025 | |||||
| g | Independiente | - | Nacional Potosí | ||
| g | Guaraní | - | Boston River | ||
| Group B | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Universidad Católica | 2 | 1 | 1 | 0 | 4 | 2 | +2 | 4 | WX-- | ||
| 2 | Vitória | 2 | 0 | 2 | 0 | 1 | 1 | +0 | 2 | OX-- | ||
| 3 | Defensa y Justicia | 2 | 0 | 2 | 0 | 0 | 0 | +0 | 2 | OO-- | ||
| 4 | Cerro Largo | 2 | 0 | 1 | 1 | 1 | 3 | -2 | 1 | LO-- | ||
| Wednesday, 2 April 2025 | |||||
| g |  Vitória | 1-1 | Universidad Católica | ||
| 76(p) | Matheus | 54 | Londoño | ||
| Thursday, 3 April 2025 | |||||
| g | Cerro Largo | 0-0 | Defensa y Justicia | ||
| Thursday, 10 April 2025 | |||||
| g | Defensa y Justicia | 0-0 | Vitória | ||
| g | Universidad Católica | 3-1 | Cerro Largo | ||
| 18 | Londoño | 75 | Ferrares | ||
| 45+1 | Díaz | ||||
| 90+4 | Díaz | ||||
| Wednesday, 23 April 2025 | |||||
| g | Vitória | - | Cerro Largo | ||
| Thursday, 24 April 2025 | |||||
| g | Universidad Católica | - | Defensa y Justicia | ||
| Tuesday, 6 May 2025 | |||||
| g | Vitória | - | Defensa y Justicia | ||
| Wednesday, 7 May 2025 | |||||
| g | Cerro Largo | - | Universidad Católica | ||
| Wednesday, 14 May 2025 | |||||
| g | Defensa y Justicia | - | Universidad Católica | ||
| g | Cerro Largo | - | Vitória | ||
| Wednesday, 28 May 2025 | |||||
| g | Defensa y Justicia | - | Cerro Largo | ||
| g | Universidad Católica | - | Vitória | ||
| Group C | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Huracán | 2 | 2 | 0 | 0 | 7 | 1 | +6 | 6 | WW-- | ||
| 2 | América | 2 | 1 | 1 | 0 | 4 | 2 | +2 | 4 | XW-- | ||
| 3 | Corinthians | 2 | 0 | 1 | 1 | 2 | 3 | -1 | 1 | XL-- | ||
| 4 | Racing | 2 | 0 | 0 | 2 | 1 | 8 | -7 | 0 | LL-- | ||
| Wednesday, 2 April 2025 | |||||
| g | Corinthians | 1-2 | Huracán | ||
| 13 | Raniele | 6 | Sequeira | ||
| 37 | Sequeira | ||||
| g | Racing | 1-3 | América | ||
| 90+2 | Da Silva | 14 | Holgado | ||
| 32 | Vergara | ||||
| 83 | Ramos | ||||
| Tuesday, 8 April 2025 | |||||
| g | América | 1-1 | Corinthians | ||
| 24 | Ramos | 81 | Matheuzinho | ||
| Wednesday, 9 April 2025 | |||||
| g | Huracán | 5-0 | Racing | ||
| 9 | Pereyra | ||||
| 20(og) | Cotugno | ||||
| 36 | De La Fuente | ||||
| 45+3 | Urzi | ||||
| 53 | Pérez | ||||
| Wednesday, 23 April 2025 | |||||
| g | Huracán | - | América | ||
| Thursday, 24 April 2025 | |||||
| g | Corinthians | - | Racing | ||
| Tuesday, 6 May 2025 | |||||
| g | Corinthians | - | América | ||
| Thursday, 8 May 2025 | |||||
| g | Racing | - | Huracán | ||
| Wednesday, 14 May 2025 | |||||
| g | América | - | Huracán | ||
| Thursday, 15 May 2025 | |||||
| g | Racing | - | Corinthians | ||
| Tuesday, 27 May 2025 | |||||
| g | América | - | Racing | ||
| g | Huracán | - | Corinthians | ||
| Group D | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Godoy Cruz | 2 | 2 | 0 | 0 | 4 | 0 | +4 | 6 | WW-- | ||
| 2 | Grêmio | 2 | 2 | 0 | 0 | 4 | 1 | +3 | 6 | WW-- | ||
| 3 | Sportivo Luqueño | 2 | 0 | 0 | 2 | 1 | 4 | -3 | 0 | LL-- | ||
| 4 | Atlético Grau | 2 | 0 | 0 | 2 | 0 | 4 | -4 | 0 | LL-- | ||
| Wednesday, 2 April 2025 | |||||
| g | Sportivo Luqueño | 1-2 | Grêmio | ||
| 29 | Santander | 17(p) | Arezo | ||
| 71 | Braithwaite | ||||
| g |  Atlético Grau | 0-2 | Godoy Cruz | ||
| 19 | Mendoza | ||||
| 55 | Fernández | ||||
| Tuesday, 8 April 2025 | |||||
| g | Grêmio | 2-0 | Atlético Grau | ||
| 37 | Arezo | ||||
| 67 | Olivera | ||||
| g | Godoy Cruz | 2-0 | Sportivo Luqueño | ||
| 30 | Mendoza | ||||
| 90+4 | Pascual | ||||
| Wednesday, 23 April 2025 | |||||
| g | Atlético Grau | - | Sportivo Luqueño | ||
| Thursday, 24 April 2025 | |||||
| g | Godoy Cruz | - | Grêmio | ||
| Tuesday, 6 May 2025 | |||||
| g | Sportivo Luqueño | - | Godoy Cruz | ||
| Wednesday, 7 May 2025 | |||||
| g | Atlético Grau | - | Grêmio | ||
| Tuesday, 13 May 2025 | |||||
| g | Grêmio | - | Godoy Cruz | ||
| g | Sportivo Luqueño | - | Atlético Grau | ||
| Thursday, 29 May 2025 | |||||
| g | Grêmio | - | Sportivo Luqueño | ||
| g | Godoy Cruz | - | Atlético Grau | ||
| Group E | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Mushuc Runa | 2 | 2 | 0 | 0 | 5 | 3 | +2 | 6 | WW-- | ||
| 2 | Palestino | 2 | 1 | 0 | 1 | 4 | 3 | +1 | 3 | WL-- | ||
| 3 | Unión | 2 | 1 | 0 | 1 | 1 | 2 | -1 | 3 | LW-- | ||
| 4 | Cruzeiro | 2 | 0 | 0 | 2 | 1 | 3 | -2 | 0 | LL-- | ||
| Tuesday, 1 April 2025 | |||||
| g | Unión | 1-0 | Cruzeiro | ||
| 90+4 | Díaz | ||||
| Thursday, 3 April 2025 | |||||
| g | Mushuc Runa | 3-2 | Palestino | ||
| 41 | Haquín | 71 | Marabel | ||
| 75 | Simisterra | 90+3 | Carrasco | ||
| 82 | Alonso | ||||
| Wednesday, 9 April 2025 | |||||
| g | Cruzeiro | 1-2 | Mushuc Runa | ||
| 67(p) | Gabriel | 29 | Orejuela | ||
| 77 | Bentaberry | ||||
| g | Palestino | 2-0 | Unión | ||
| 12(p) | Carrasco | ||||
| 90+5 | Marabel | ||||
| Wednesday, 23 April 2025 | |||||
| g | Mushuc Runa | - | Unión | ||
| Thursday, 24 April 2025 | |||||
| g | Palestino | - | Cruzeiro | ||
| Wednesday, 7 May 2025 | |||||
| g | Unión | - | Palestino | ||
| g | Mushuc Runa | - | Cruzeiro | ||
| Tuesday, 13 May 2025 | |||||
| g | Unión | - | Mushuc Runa | ||
| Wednesday, 14 May 2025 | |||||
| g | Cruzeiro | - | Palestino | ||
| Wednesday, 28 May 2025 | |||||
| g | Cruzeiro | - | Unión | ||
| g | Palestino | - | Mushuc Runa | ||
| Group F | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Fluminense | 2 | 2 | 0 | 0 | 6 | 0 | +6 | 6 | WW-- | ||
| 2 | Once Caldas | 2 | 1 | 0 | 1 | 2 | 1 | +1 | 3 | WL-- | ||
| 3 | Unión Española | 2 | 0 | 1 | 1 | 1 | 3 | -2 | 1 | LX-- | ||
| 4 | GV San José | 2 | 0 | 1 | 1 | 1 | 6 | -5 | 1 | LX-- | ||
| Tuesday, 1 April 2025 | |||||
| g | Once Caldas | 0-1 | Fluminense | ||
| 31 | Cano | ||||
| Thursday, 3 April 2025 | |||||
| g | GV San José | 1-1 | Unión Española | ||
| 88 | López Pissano | 82 | Núñez | ||
| Wednesday, 9 April 2025 | |||||
| g | Unión Española | 0-2 | Once Caldas | ||
| 57 | Moreno | ||||
| 86 | García | ||||
| Thursday, 10 April 2025 | |||||
| g | Fluminense | 5-0 | GV San José | ||
| 20 | Everaldo | ||||
| 44 | Everaldo | ||||
| 60 | Serna | ||||
| 73 | Cano | ||||
| 79 | Cano | ||||
| Tuesday, 22 April 2025 | |||||
| g | Unión Española | - | Fluminense | ||
| g | GV San José | - | Once Caldas | ||
| Thursday, 8 May 2025 | |||||
| g | Once Caldas | - | Unión Española | ||
| g | GV San José | - | Fluminense | ||
| Wednesday, 14 May 2025 | |||||
| g | Fluminense | - | Unión Española | ||
| Thursday, 15 May 2025 | |||||
| g | Once Caldas | - | GV San José | ||
| Thursday, 29 May 2025 | |||||
| g | Fluminense | - | Once Caldas | ||
| g | Unión Española | - | GV San José | ||
| Group G | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Lanús | 2 | 1 | 1 | 0 | 5 | 2 | +3 | 4 | WX-- | ||
| 2 | Vasco da Gama | 2 | 1 | 1 | 0 | 4 | 3 | +1 | 4 | WX-- | ||
| 3 | Puerto Cabello | 2 | 0 | 1 | 1 | 2 | 3 | -1 | 1 | LX-- | ||
| 4 | FBC Melgar | 2 | 0 | 1 | 1 | 3 | 6 | -3 | 1 | LX-- | ||
| Wednesday, 2 April 2025 | |||||
| g | FBC Melgar | 3-3 | Vasco da Gama | ||
| 39 | Rodríguez | 3 | Philippe Coutinho | ||
| 80 | Castro | 32 | Vegetti | ||
| 90 | Cabrera | 52 | Vegetti | ||
| Thursday, 3 April 2025 | |||||
| g |  Puerto Cabello | 2-2 | Lanús | ||
| 15 | Paredes | 70 | Canelo | ||
| 51 | Awudu | 76 | Aquino | ||
| Tuesday, 8 April 2025 | |||||
| g | Vasco da Gama | 1-0 | Puerto Cabello | ||
| 45+2 | Vegetti | ||||
| Wednesday, 9 April 2025 | |||||
| g | Lanús | 3-0 | FBC Melgar | ||
| 45+1 | Moreno | ||||
| 47 | Salvio | ||||
| 79 | Orozco | ||||
| Tuesday, 22 April 2025 | |||||
| g | Vasco da Gama | - | Lanús | ||
| g | FBC Melgar | - | Puerto Cabello | ||
| Tuesday, 6 May 2025 | |||||
| g | FBC Melgar | - | Lanús | ||
| Wednesday, 7 May 2025 | |||||
| g | Puerto Cabello | - | Vasco da Gama | ||
| Tuesday, 13 May 2025 | |||||
| g | Lanús | - | Vasco da Gama | ||
| g | Puerto Cabello | - | FBC Melgar | ||
| Tuesday, 27 May 2025 | |||||
| g | Vasco da Gama | - | FBC Melgar | ||
| g | Lanús | - | Puerto Cabello | ||
| Group H | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | Atlético-MG | 2 | 1 | 1 | 0 | 4 | 0 | +4 | 4 | WO-- | ||
| 2 | Caracas | 2 | 1 | 1 | 0 | 4 | 3 | +1 | 4 | XW-- | ||
| 3 | Cienciano | 2 | 0 | 2 | 0 | 2 | 2 | +0 | 2 | XO-- | ||
| 4 | Deportes Iquique | 2 | 0 | 0 | 2 | 1 | 6 | -5 | 0 | LL-- | ||
| Tuesday, 1 April 2025 | |||||
| g | Cienciano | 0-0 | Atlético-MG | ||
| g | Deportes Iquique | 1-2 | Caracas | ||
| 4(p) | Puch | 33 | Echenique | ||
| 37 | Aguilar | ||||
| Tuesday, 8 April 2025 | |||||
| g | Caracas | 2-2 | Cienciano | ||
| 8 | Reinoso | 41 | Garcés | ||
| 90+9 | Rondón | 67 | Garcés | ||
| Thursday, 10 April 2025 | |||||
| g | Atlético-MG | 4-0 | Deportes Iquique | ||
| 1 | Rony | ||||
| 11(p) | Hulk | ||||
| 35 | Natanael | ||||
| 66(p) | Gustavo Scarpa | ||||
| Wednesday, 23 April 2025 | |||||
| g | Caracas | - | Atlético-MG | ||
| Thursday, 24 April 2025 | |||||
| g | Deportes Iquique | - | Cienciano | ||
| Thursday, 8 May 2025 | |||||
| g | Cienciano | - | Caracas | ||
| g | Deportes Iquique | - | Atlético-MG | ||
| Thursday, 15 May 2025 | |||||
| g | Atlético-MG | - | Caracas | ||
| g | Cienciano | - | Deportes Iquique | ||
| Thursday, 29 May 2025 | |||||
| g | Atlético-MG | - | Cienciano | ||
| g | Caracas | - | Deportes Iquique | ||
| 3 | +1 | Ender ECHENIQUE (Caracas) |
| +2 | Bryan CARRASCO (Palestino) | |
| +3 | Pablo VEGETTI (Vasco da Gama) | |
| +3 | Germán CANO (Fluminense) | |
| 2 | Mauricio AFFONSO (Cerro Largo) | |
| +1 | Renny SIMISTERRA (Mushuc Runa) | |
| +2 | Mateo MENDOZA (Godoy Cruz) | |
| +2 | Carlos GARCÉS (Cienciano) | |
| Guillermo PAIVA (Junior) | ||
| +2 | Luis RAMOS (América) | |
| +2 | Leonardo SEQUEIRA (Huracán) | |
| +1 | William MENDIETA (Guaraní) | |
| +2 | Pablo GALDAMES (Independiente) | |
| +2 | Júnior MARABEL (Palestino) | |
| +2 | Douglas AREZO (Grêmio) | |
| +2 | Ismael DÍAZ (Universidad Católica) | |
| +2 | EVERALDO Stum (Fluminense) | |
| Juan RAMÍREZ (Everton) | ||
| +2 | Fernando FERNÁNDEZ (Guaraní) | |
| +1 | Junior PAREDES (Puerto Cabello) | |
| +1 | Bryan BENTABERRY (Mushuc Runa) | |
| +1 | Duván VERGARA (América) | |
| +2 | Azarías LONDOÑO (Universidad Católica) |
