| ROUND | C | P | Q1 | Q2 | Q3 | Q4 | R1 | R2 | QF | SF | F | |||||||||||||
| sf | f | l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | r1 | r2 | r3 | r4 | r5 | r6 | l1 | l2 | l1 | l2 | l1 | l2 | |||
| Season archive |
| Tuesday, 6 July 2021 | ||||||
| q1l1 |  HJK | 3-1 | Budućnost | |||
| q1l1 |  Ferencváros | 3-0 | Prishtina | |||
| q1l1 |  Flora | 2-0 | Hibernians | |||
| q1l1 |  Žalgiris | 3-1 | Linfield | |||
| q1l1 |  CFR Cluj | 3-1 | Borac Banja Luka | |||
| q1l1 |  Shkëndija | 0-1 | Mura | |||
| q1l1 |  Fola | 2-2 | Lincoln Red Imps | |||
| Wednesday, 7 July 2021 | ||||||
| q1l1 |  Slovan Bratislava | 2-0 | Shamrock Rovers | |||
| q1l1 |  Malmö FF | 1-0 | Rīga | |||
| q1l1 |  Dinamo Zagreb | 3-2 | Valur | |||
| q1l1 |  Bodø/Glimt | 2-3 | Legia Warszawa | |||
| q1l1 |  Maccabi Haifa | 1-1 | Kairat | |||
| q1l1 |  Dinamo Tbilisi | 1-2 | Neftçi | |||
| q1l1 |  Connah's Quay | 2-2 | Alashkert | |||
| q1l1 |  Teuta | 0-4 | Sheriff | |||
| q1l1 |  Ludogorets | 1-0 | Shakhter | |||
| Tuesday, 13 July 2021 | ||||||
| q1l2 | Shamrock Rovers | 2-1 | Slovan Bratislava | 2-3 | ||
| q1l2 | Linfield | 1-2 | Žalgiris | 2-5 | ||
| q1l2 | Valur | 0-2 | Dinamo Zagreb | 2-5 | ||
| q1l2 | Sheriff | 1-0 | Teuta | 5-0 | ||
| q1l2 | Mura | 5-0 | Shkëndija | 6-0 | ||
| q1l2 | Hibernians | 0-3 | Flora | 0-5 | ||
| q1l2 | Borac Banja Luka | 2-1 | CFR Cluj | 3-4, aet | ||
| q1l2 | Shakhter | 0-1 | Ludogorets | 0-2 | ||
| q1l2 | Budućnost | 0-4 | HJK | 1-7 | ||
| q1l2 | Prishtina | 1-3 | Ferencváros | 1-6 | ||
| q1l2 | Lincoln Red Imps | 5-0 | Fola | 7-2 | ||
| q1l2 | Rīga | 1-1 | Malmö FF | 1-2 | ||
| Wednesday, 14 July 2021 | ||||||
| q1l2 | Legia Warszawa | 2-0 | Bodø/Glimt | 5-2 | ||
| q1l2 | Neftçi | 2-1 | Dinamo Tbilisi | 4-2 | ||
| q1l2 | Kairat | 2-0 | Maccabi Haifa | 3-1 | ||
| q1l2 | Alashkert | 1-0 | Connah's Quay | 3-2, aet | ||
