| ROUND | C | P | Q1 | Q2 | Q3 | Q4 | R1 | R2 | QF | SF | F | |||||||||||||
| sf | f | l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | r1 | r2 | r3 | r4 | r5 | r6 | l1 | l2 | l1 | l2 | l1 | l2 | |||
| Season archive |
| Tuesday, 20 July 2021 | ||||||
| q2l1 |  Celtic | 1-1 | FC Midtjylland | |||
| q2l1 |  Ferencváros | 2-0 | Žalgiris | |||
| q2l1 |  Dinamo Zagreb | 2-0 | Omonia | |||
| q2l1 |  SK Rapid Wien | 2-1 | Sparta Praha | |||
| q2l1 |  Alashkert | 0-1 | Sheriff | |||
| q2l1 |  Lincoln Red Imps | 1-2 | CFR Cluj | |||
| Wednesday, 21 July 2021 | ||||||
| q2l1 |  Legia Warszawa | 2-1 | Flora | |||
| q2l1 |  Slovan Bratislava | 0-0 | Young Boys | |||
| q2l1 |  PSV | 5-1 | Galatasaray | |||
| q2l1 |  Olympiakos | 1-0 | Neftçi | |||
| q2l1 |  Malmö FF | 2-1 | HJK | |||
| q2l1 |  Mura | 0-0 | Ludogorets | |||
| q2l1 |  Kairat | 2-1 | Crvena Zvezda | |||
| Tuesday, 27 July 2021 | ||||||
| q2l2 | Omonia | 0-1 | Dinamo Zagreb | 0-3 | ||
| q2l2 | HJK | 2-2 | Malmö FF | 3-4 | ||
| q2l2 | Flora | 0-1 | Legia Warszawa | 1-3 | ||
| q2l2 | Žalgiris | 1-3 | Ferencváros | 1-5 | ||
| Wednesday, 28 July 2021 | ||||||
| q2l2 | Young Boys | 3-2 | Slovan Bratislava | 3-2 | ||
| q2l2 | Galatasaray | 1-2 | PSV | 2-7 | ||
| q2l2 | Sparta Praha | 2-0 | SK Rapid Wien | 3-2 | ||
| q2l2 | Crvena Zvezda | 5-0 | Kairat | 6-2 | ||
| q2l2 | Sheriff | 3-1 | Alashkert | 4-1 | ||
| q2l2 | Neftçi | 0-1 | Olympiakos | 0-2 | ||
| q2l2 | FC Midtjylland | 2-1 | Celtic | 3-2, aet | ||
| q2l2 | CFR Cluj | 2-0 | Lincoln Red Imps | 4-1 | ||
| q2l2 | Ludogorets | 3-1 | Mura | 3-1 | ||
