| ROUND | Q1 | Q2 | Q3 | R1 | QF | |||||||||
| l1 | l2 | l1 | l2 | l1 | l2 | r1 | r2 | r3 | r4 | r5 | r6 | l1 | l2 | |
| Season archive |
| Group 1 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
 | 1 |  | Palmeiras | 6 | 5 | 0 | 1 | 20 | 7 | +13 | 15 | WLWW |
| 2 | | Defensa y Justicia | 6 | 2 | 3 | 1 | 11 | 8 | +3 | 9 | XWXL |
| 3 | | Independiente | 6 | 1 | 2 | 3 | 8 | 11 | -3 | 5 | XLLW | |
| 4 | | Universitario | 6 | 1 | 1 | 4 | 6 | 19 | -13 | 4 | LWXL | |
| Wednesday, 21 April 2021 | |||||
| 1 |  Universitario | 2-3 | Palmeiras | ||
| 1 |  Independiente | 1-1 | Defensa y Justicia | ||
| Tuesday, 27 April 2021 | |||||
| 2 | Palmeiras | 5-0 | Independiente | ||
| Wednesday, 28 April 2021 | |||||
| 2 | Defensa y Justicia | 3-0 | Universitario | ||
| Tuesday, 4 May 2021 | |||||
| 3 | Defensa y Justicia | 1-2 | Palmeiras | ||
| Wednesday, 5 May 2021 | |||||
| 3 | Independiente | 4-0 | Universitario | ||
| Tuesday, 11 May 2021 | |||||
| 4 | Independiente | 0-1 | Palmeiras | ||
| Wednesday, 12 May 2021 | |||||
| 4 | Universitario | 1-1 | Defensa y Justicia | ||
| Tuesday, 18 May 2021 | |||||
| 5 | Palmeiras | 3-4 | Defensa y Justicia | ||
| 5 | Universitario | 3-2 | Independiente | ||
| Thursday, 27 May 2021 | |||||
| 6 | Palmeiras | 6-0 | Universitario | ||
| 6 | Defensa y Justicia | 1-1 | Independiente | ||
| Group 2 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Internacional | 6 | 3 | 1 | 2 | 12 | 5 | +7 | 10 | OWLW |
| 2 | | Olimpia | 6 | 3 | 0 | 3 | 13 | 14 | -1 | 9 | WLWL |
| 3 | | Deportivo Táchira | 6 | 3 | 0 | 3 | 14 | 17 | -3 | 9 | LWWL | |
| 4 | | Always Ready | 6 | 2 | 1 | 3 | 8 | 11 | -3 | 7 | OLLW | |
| Tuesday, 20 April 2021 | |||||
| 1 |  Deportivo Táchira | 3-2 | Olimpia | ||
| 1 |  Always Ready | 2-0 | Internacional | ||
| Tuesday, 27 April 2021 | |||||
| 2 | Internacional | 4-0 | Deportivo Táchira | ||
| Wednesday, 28 April 2021 | |||||
| 2 | Olimpia | 2-1 | Always Ready | ||
| Wednesday, 5 May 2021 | |||||
| 3 | Internacional | 6-1 | Olimpia | ||
| Thursday, 6 May 2021 | |||||
| 3 | Always Ready | 2-0 | Deportivo Táchira | ||
| Tuesday, 11 May 2021 | |||||
| 4 | Deportivo Táchira | 2-1 | Internacional | ||
| Thursday, 13 May 2021 | |||||
| 4 | Always Ready | 1-2 | Olimpia | ||
| Wednesday, 19 May 2021 | |||||
| 5 | Deportivo Táchira | 7-2 | Always Ready | ||
| Thursday, 20 May 2021 | |||||
| 5 | Olimpia | 0-1 | Internacional | ||
| Wednesday, 26 May 2021 | |||||
| 6 | Olimpia | 6-2 | Deportivo Táchira | ||
| 6 | Internacional | 0-0 | Always Ready | ||
| Group 3 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Barcelona | 6 | 4 | 1 | 1 | 10 | 3 | +7 | 13 | WOLW |
| 2 | | Boca Juniors | 6 | 3 | 1 | 2 | 6 | 2 | +4 | 10 | WOLL |
| 3 | | Santos | 6 | 2 | 0 | 4 | 8 | 9 | -1 | 6 | LLWW | |
| 4 | | Strongest | 6 | 2 | 0 | 4 | 4 | 14 | -10 | 6 | LWWL | |
| Tuesday, 20 April 2021 | |||||
| 1 | Santos | 0-2 | Barcelona | ||
| Wednesday, 21 April 2021 | |||||
| 1 | Strongest | 0-1 | Boca Juniors | ||
| Tuesday, 27 April 2021 | |||||
| 2 | Boca Juniors | 2-0 | Santos | ||
| Wednesday, 28 April 2021 | |||||
| 2 | Barcelona | 4-0 | Strongest | ||
| Tuesday, 4 May 2021 | |||||
| 3 | Santos | 5-0 | Strongest | ||
| 3 | Barcelona | 1-0 | Boca Juniors | ||
| Tuesday, 11 May 2021 | |||||
| 4 | Santos | 1-0 | Boca Juniors | ||
| 4 | Strongest | 2-0 | Barcelona | ||
| Tuesday, 18 May 2021 | |||||
| 5 | Strongest | 2-1 | Santos | ||
| Thursday, 20 May 2021 | |||||
| 5 | Boca Juniors | 0-0 | Barcelona | ||
| Wednesday, 26 May 2021 | |||||
| 6 | Boca Juniors | 3-0 | Strongest | ||
| 6 | Barcelona | 3-1 | Santos | ||
| Group 4 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Fluminense | 6 | 3 | 2 | 1 | 10 | 7 | +3 | 11 | WLWX |
| 2 | | River Plate | 6 | 2 | 3 | 1 | 7 | 7 | +0 | 9 | LWXO |
| 3 | | Junior | 6 | 1 | 4 | 1 | 6 | 6 | +0 | 7 | OWXX | |
| 4 | | Santa Fé | 6 | 0 | 3 | 3 | 4 | 7 | -3 | 3 | OLLO | |
| Thursday, 22 April 2021 | |||||
| 1 | Fluminense | 1-1 | River Plate | ||
| 1 |  Junior | 1-1 | Santa Fé | ||
| Wednesday, 28 April 2021 | |||||
| 2 | River Plate | 2-1 | Junior | ||
| 2 | Santa Fé | 1-2 | Fluminense | ||
| Thursday, 6 May 2021 | |||||
| 3 | Santa Fé | 0-0 | River Plate | ||
| 3 | Junior | 1-1 | Fluminense | ||
| Wednesday, 12 May 2021 | |||||
| 4 | Fluminense | 2-1 | Santa Fé | ||
| 4 | Junior | 1-1 | River Plate | ||
| Tuesday, 18 May 2021 | |||||
| 5 | Fluminense | 1-2 | Junior | ||
| Wednesday, 19 May 2021 | |||||
| 5 | River Plate | 2-1 | Santa Fé | ||
| Tuesday, 25 May 2021 | |||||
| 6 | River Plate | 1-3 | Fluminense | ||
| 6 | Santa Fé | 0-0 | Junior | ||
| Group 5 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Racing Club | 6 | 4 | 2 | 0 | 9 | 2 | +7 | 14 | WWWO |
| 2 | | São Paulo | 6 | 3 | 2 | 1 | 9 | 2 | +7 | 11 | WLXO |
| 3 | | Sporting Cristal | 6 | 1 | 1 | 4 | 3 | 10 | -7 | 4 | LWLO | |
| 4 | | Rentistas | 6 | 0 | 3 | 3 | 2 | 9 | -7 | 3 | LLXO | |
| Tuesday, 20 April 2021 | |||||
| 1 | Sporting Cristal | 0-3 | São Paulo | ||
| Wednesday, 21 April 2021 | |||||
| 1 |  Rentistas | 1-1 | Racing Club | ||
| Thursday, 29 April 2021 | |||||
| 2 | São Paulo | 2-0 | Rentistas | ||
| 2 | Racing Club | 2-1 | Sporting Cristal | ||
| Wednesday, 5 May 2021 | |||||
| 3 | Racing Club | 0-0 | São Paulo | ||
| 3 | Rentistas | 0-0 | Sporting Cristal | ||
| Tuesday, 11 May 2021 | |||||
| 4 | Sporting Cristal | 0-2 | Racing Club | ||
| Wednesday, 12 May 2021 | |||||
| 4 | Rentistas | 1-1 | São Paulo | ||
| Tuesday, 18 May 2021 | |||||
| 5 | São Paulo | 0-1 | Racing Club | ||
| Wednesday, 19 May 2021 | |||||
| 5 | Sporting Cristal | 2-0 | Rentistas | ||
| Tuesday, 25 May 2021 | |||||
| 6 | São Paulo | 3-0 | Sporting Cristal | ||
| 6 | Racing Club | 3-0 | Rentistas | ||
| Group 6 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Argentinos Juniors | 6 | 4 | 0 | 2 | 7 | 3 | +4 | 12 | LWLW |
| 2 | | Universidad Católica | 6 | 3 | 0 | 3 | 6 | 6 | +0 | 9 | WLWW |
| 3 | | Nacional | 6 | 2 | 2 | 2 | 8 | 9 | -1 | 8 | WWOL | |
| 4 | | Nacional | 6 | 1 | 2 | 3 | 6 | 9 | -3 | 5 | LLOL | |
| Tuesday, 20 April 2021 | |||||
| 1 | Argentinos Juniors | 2-0 | Nacional | ||
| Thursday, 22 April 2021 | |||||
| 1 | Nacional | 2-0 | Universidad Católica | ||
| Wednesday, 28 April 2021 | |||||
| 2 | Nacional | 4-4 | Nacional | ||
| Thursday, 29 April 2021 | |||||
| 2 | Universidad Católica | 0-2 | Argentinos Juniors | ||
| Wednesday, 5 May 2021 | |||||
| 3 | Universidad Católica | 3-1 | Nacional | ||
| Thursday, 6 May 2021 | |||||
| 3 | Nacional | 0-2 | Argentinos Juniors | ||
| Wednesday, 12 May 2021 | |||||
| 4 | Argentinos Juniors | 0-1 | Universidad Católica | ||
| 4 | Nacional | 0-0 | Nacional | ||
| Tuesday, 18 May 2021 | |||||
| 5 | Nacional | 1-0 | Universidad Católica | ||
| Thursday, 20 May 2021 | |||||
| 5 | Argentinos Juniors | 1-0 | Nacional | ||
| Wednesday, 26 May 2021 | |||||
| 6 | Nacional | 2-0 | Argentinos Juniors | ||
| 6 | Universidad Católica | 2-0 | Nacional | ||
| Group 7 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Flamengo | 6 | 3 | 3 | 0 | 14 | 9 | +5 | 12 | OXXW |
| 2 | | Vélez Sársfield | 6 | 3 | 1 | 2 | 10 | 8 | +2 | 10 | OWWW |
| 3 | | LDU Quito | 6 | 2 | 2 | 2 | 15 | 13 | +2 | 8 | WXLL | |
| 4 | | Unión La Calera | 6 | 0 | 2 | 4 | 8 | 17 | -9 | 2 | LLXL | |
| Tuesday, 20 April 2021 | |||||
| 1 | Vélez Sársfield | 2-3 | Flamengo | ||
| Wednesday, 21 April 2021 | |||||
| 1 | Unión La Calera | 2-2 | LDU Quito | ||
| Tuesday, 27 April 2021 | |||||
| 2 | Flamengo | 4-1 | Unión La Calera | ||
| 2 | LDU Quito | 3-1 | Vélez Sársfield | ||
| Tuesday, 4 May 2021 | |||||
| 3 | LDU Quito | 2-3 | Flamengo | ||
| 3 | Unión La Calera | 0-2 | Vélez Sársfield | ||
| Tuesday, 11 May 2021 | |||||
| 4 | Unión La Calera | 2-2 | Flamengo | ||
| Thursday, 13 May 2021 | |||||
| 4 | Vélez Sársfield | 3-1 | LDU Quito | ||
| Wednesday, 19 May 2021 | |||||
| 5 | Flamengo | 2-2 | LDU Quito | ||
| 5 | Vélez Sársfield | 2-1 | Unión La Calera | ||
| Thursday, 27 May 2021 | |||||
| 6 | Flamengo | 0-0 | Vélez Sársfield | ||
| 6 | LDU Quito | 5-2 | Unión La Calera | ||
| Group 8 | Overall | |||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | ||||
| 1 | | Atlético-MG | 6 | 5 | 1 | 0 | 15 | 3 | +12 | 16 | WWWW |
| 2 | | Cerro Porteño | 6 | 3 | 1 | 2 | 4 | 5 | -1 | 10 | WLWL |
| 3 | | América | 6 | 1 | 1 | 4 | 5 | 9 | -4 | 4 | LWLO | |
| 4 | | Deportivo La Guaira | 6 | 0 | 3 | 3 | 2 | 9 | -7 | 3 | LLLO | |
| Wednesday, 21 April 2021 | |||||
| 1 | América | 0-2 | Cerro Porteño | ||
| 1 | Deportivo La Guaira | 1-1 | Atlético-MG | ||
| Tuesday, 27 April 2021 | |||||
| 2 | Atlético-MG | 2-1 | América | ||
| Wednesday, 28 April 2021 | |||||
| 2 | Cerro Porteño | 0-0 | Deportivo La Guaira | ||
| Tuesday, 4 May 2021 | |||||
| 3 | Atlético-MG | 4-0 | Cerro Porteño | ||
| Thursday, 6 May 2021 | |||||
| 3 | Deportivo La Guaira | 0-0 | América | ||
| Wednesday, 12 May 2021 | |||||
| 4 | Deportivo La Guaira | 0-1 | Cerro Porteño | ||
| Thursday, 13 May 2021 | |||||
| 4 | América | 1-3 | Atlético-MG | ||
| Wednesday, 19 May 2021 | |||||
| 5 | América | 3-1 | Deportivo La Guaira | ||
| 5 | Cerro Porteño | 0-1 | Atlético-MG | ||
| Tuesday, 25 May 2021 | |||||
| 6 | Atlético-MG | 4-0 | Deportivo La Guaira | ||
| 6 | Cerro Porteño | 1-0 | América | ||
| 6 | +6 | GABRIEL Barbosa (Flamengo, 3p) |
| +6 | HULK (Atlético-MG, 1p) | |
| +6 | RONY (Palmeiras) | |
| 5 | +5 | Tomás CHANCALAY (Racing Club) |
| 4 | +4 | THIAGO GALHARDO do Nascimento (Internacional, 1p) |
| +4 | Billy ARCE (LDU Quito) | |
| +4 | Walter BOU (Defensa y Justicia, 1p) | |
| +4 | FRED (Fluminense) | |
| +4 | Gonzalo BERGESSIO (Nacional) | |
| 3 | +3 | Miguel BORJA (Junior, 1p) |
| +3 | Richard ORTIZ (Olimpia) | |
| +3 | Sebastián VILLA (Boca Juniors) | |
| +3 | Luis AMARILLA (LDU Quito) | |
| +3 | Jhon SÁNCHEZ (Independiente) | |
| +3 | Sebastián SÁEZ (Unión La Calera) | |
| +3 | Jair REINOSO (Strongest) | |
| +3 | Cristian BORJA (LDU Quito) | |
| +3 | Gabriel ÁVALOS (Argentinos Juniors) | |
| +3 | YURI ALBERTO Monteiro (Internacional) | |
| +3 | Brian ROMERO (Defensa y Justicia) | |
| +3 | Christian ORTIZ (Independiente) | |
| +3 | Lucas JANSON (Vélez Sársfield) | |
| +3 | Freddy GÓNDOLA (Deportivo Táchira) | |
| +3 | Carlos GARCÉS (Barcelona) |
