| ROUND | Q1 | Q2 | Q3 | Q4 | R1 | R2 | R3 | QF | SF | F | |||||||||||||
| l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | r1 | r2 | r3 | r4 | r5 | r6 | l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | ||
| Season archive |
| Tuesday, 5 July 2022 | ||||||
| q1l1 |  Gżira United | 1-1 | Atlètic Club d'Escaldes | |||
| q1l1 |  St Joseph's | 0-0 | Larne | |||
| Wednesday, 6 July 2022 | ||||||
| q1l1 |  FC Inter | 1-0 | Drita | |||
| q1l1 |  Víkingur | 1-0 | Europa FC | |||
| Thursday, 7 July 2022 | ||||||
| q1l1 |  Dinamo Tbilisi | 2-3 | Paide Linnameeskond | |||
| q1l1 |  Dunajská Streda | 2-1 | Cliftonville | |||
| q1l1 |  Dinamo Minsk | 1-1 | Dečić | |||
| q1l1 |  Pogoń Szczecin | 4-1 | KR | |||
| q1l1 | Flora | 1-0 | Seinäjoen JK | |||
| q1l1 |  Olimpija | 1-1 | FC Differdange 03 | |||
| q1l1 | HB | 1-0 | Newtown | |||
| q1l1 | Floriana | 0-0 | Petrocub | |||
| q1l1 |  Tre Penne | 0-2 | Tuzla City | |||
| q1l1 |  Derry City | 0-2 | Rīga | |||
| q1l1 | Ružomberok | 2-0 | Kauno Žalgiris | |||
| q1l1 | Lechia Gdańsk | 4-1 | AP Brera | |||
| q1l1 | Borac Banja Luka | 2-0 | B36 | |||
| q1l1 | KuPS | 2-0 | Dila Gori | |||
| q1l1 | Budućnost | 2-0 | Llapi | |||
| q1l1 |  Laçi | 0-0 | Iskra | |||
| q1l1 | Shkëndija | 2-0 | Ararat | |||
| q1l1 | Fola | 0-1 | Tre Fiori | |||
| q1l1 | Sfântul Gheorghe | 1-2 | Mura | |||
| q1l1 | Bala Town | 1-2 | Sligo Rovers | |||
| q1l1 | UE Santa Coloma | 0-1 | Breiðablik | |||
| q1l1 | Alashkert | 1-0 | Hamrun Spartans | |||
| q1l1 | Iberia 1999 | 0-1 | Partizani | |||
| q1l1 | Gjilani | 1-0 | FK Liepāja | |||
| q1l1 | Bruno's Magpies | 2-1 | Crusaders | |||
| q1l1 | Panevėžys | 0-0 | Milsami | |||
| Tuesday, 12 July 2022 | ||||||
| q1l2 | Drita | 3-0 | FC Inter | 3-1 | ||
| Thursday, 14 July 2022 | ||||||
| q1l2 | KR | 1-0 | Pogoń Szczecin | 2-4 | ||
| q1l2 | Sligo Rovers | 0-1 | Bala Town | 2-2, aet, p4-3 | ||
| q1l2 | B36 | 3-1 | Borac Banja Luka | 3-3, aet, p4-3 | ||
| q1l2 | Cliftonville | 0-3 | Dunajská Streda | 1-5 | ||
| q1l2 | FK Liepāja | 3-1 | Gjilani | 3-2 | ||
| q1l2 | Ararat | 2-2 | Shkëndija | 2-4 | ||
| q1l2 | Partizani | 0-1 | Iberia 1999 | 1-1, aet, p4-5 | ||
| q1l2 | Dila Gori | 0-0 | KuPS | 0-2 | ||
| q1l2 | Mura | 2-1 | Sfântul Gheorghe | 4-2 | ||
| q1l2 | Hamrun Spartans | 4-1 | Alashkert | 4-2 | ||
| q1l2 | Tre Fiori | 3-1 | Fola | 4-1 | ||
| q1l2 | Breiðablik | 4-1 | UE Santa Coloma | 5-1 | ||
| q1l2 | Seinäjoen JK | 4-2 | Flora | 4-3, aet | ||
| q1l2 | Crusaders | 3-1 | Bruno's Magpies | 4-3 | ||
| q1l2 | Newtown | 2-1 | HB | 2-2, aet, p4-2 | ||
| q1l2 | Larne | 0-1 | St Joseph's | 0-1 | ||
| q1l2 | FC Differdange 03 | 1-2 | Olimpija | 2-3, aet | ||
| q1l2 | Dečić | 1-2 | Dinamo Minsk | 2-3 | ||
| q1l2 | Paide Linnameeskond | 1-2 | Dinamo Tbilisi | 4-4, aet, p6-5 | ||
| q1l2 | Milsami | 2-0 | Panevėžys | 2-0 | ||
| q1l2 | Iskra | 0-1 | Laçi | 0-1 | ||
| q1l2 | Europa FC | 1-2 | Víkingur | 1-3 | ||
| q1l2 | Kauno Žalgiris | 0-0 | Ružomberok | 0-2 | ||
| q1l2 | Petrocub | 1-0 | Floriana | 1-0 | ||
| q1l2 | Rīga | 2-0 | Derry City | 4-0 | ||
| q1l2 | AP Brera | 1-2 | Lechia Gdańsk | 2-6 | ||
| q1l2 | Tuzla City | 6-0 | Tre Penne | 8-0 | ||
| q1l2 | Llapi | 2-2 | Budućnost | 2-4 | ||
| q1l2 | Atlètic Club d'Escaldes | 0-1 | Gżira United | 1-2, aet | ||
