| ROUND | Q3 | Q4 | R1 | R2 | R3 | QF | SF | F | |||||||||||
| l1 | l2 | l1 | l2 | r1 | r2 | r3 | r4 | r5 | r6 | l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | ||
| Season archive |
| Tuesday, 17 August 2021 | ||||||
| q4l1 |  Crvena Zvezda | 4-0 | CFR Cluj | |||
| Wednesday, 18 August 2021 | ||||||
| q4l1 |  Celtic | 2-0 | AZ | |||
| Thursday, 19 August 2021 | ||||||
| q4l1 |  Omonia | 4-2 | Antwerp | |||
| q4l1 |  Fenerbahçe | 1-0 | HJK | |||
| q4l1 | Rangers | 1-0 | Alashkert | |||
| q4l1 |  Olympiakos | 3-0 | Slovan Bratislava | |||
| q4l1 |  Slavia Praha | 2-2 | Legia Warszawa | |||
| q4l1 |  SK Rapid Wien | 3-0 | Zorya | |||
| q4l1 |  Mura | 1-3 | SK Sturm Graz | |||
| q4l1 |  Randers | 1-1 | Galatasaray | |||
| Thursday, 26 August 2021 | ||||||
| q4l2 | Antwerp | 2-0 | Omonia | 4-4, aet, p3-2 | ||
| q4l2 | AZ | 2-1 | Celtic | 2-3 | ||
| q4l2 | Legia Warszawa | 2-1 | Slavia Praha | 4-3 | ||
| q4l2 | Galatasaray | 2-1 | Randers | 3-2 | ||
| q4l2 | Slovan Bratislava | 2-2 | Olympiakos | 2-5 | ||
| q4l2 | HJK | 2-5 | Fenerbahçe | 2-6 | ||
| q4l2 | SK Sturm Graz | 2-0 | Mura | 5-1 | ||
| q4l2 | Zorya | 2-3 | SK Rapid Wien | 2-6 | ||
| q4l2 | CFR Cluj | 1-2 | Crvena Zvezda | 1-6 | ||
| q4l2 | Alashkert | 0-0 | Rangers | 0-1 | ||
