| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 267 | 727 | 2.72 | 143 | 53.56% | 61 | 22.85% | 63 | 23.60% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | D.C. United | 28 | 13 | 5 | 10 | 35 | 34 | +1 | 44 | LLLW | 14 | 9 | 3 | 2 | 27 | 18 | 14 | 4 | 2 | 8 | 8 | 16 | ||
| 2 | 1 | New York Red Bulls | 25 | 12 | 6 | 7 | 43 | 28 | +15 | 42 | WLWW | 12 | 8 | 2 | 2 | 22 | 8 | 13 | 4 | 4 | 5 | 21 | 20 | |
| 3 | 1 | Columbus Crew | 27 | 11 | 8 | 8 | 45 | 44 | +1 | 41 | WWXW | 14 | 8 | 4 | 2 | 32 | 20 | 13 | 3 | 4 | 6 | 13 | 24 | |
| 4 | 1 | New England Revolution | 27 | 11 | 7 | 9 | 38 | 36 | +2 | 40 | WWWW | 14 | 8 | 5 | 1 | 24 | 9 | 13 | 3 | 2 | 8 | 14 | 27 | |
| 5 | 1 | Toronto FC | 26 | 11 | 4 | 11 | 45 | 44 | +1 | 37 | LWWL | 11 | 7 | 1 | 3 | 22 | 12 | 15 | 4 | 3 | 8 | 23 | 32 | |
| 6 | 1 | Montréal Impact | 24 | 9 | 4 | 11 | 34 | 37 | -3 | 31 | WLLL | 13 | 7 | 2 | 4 | 23 | 15 | 11 | 2 | 2 | 7 | 11 | 22 | |
| 7 | 2 | Philadelphia Union | 28 | 8 | 6 | 14 | 35 | 45 | -10 | 30 | WLWX | 14 | 5 | 3 | 6 | 18 | 17 | 14 | 3 | 3 | 8 | 17 | 28 | |
| 8 | 2 | Orlando City | 28 | 7 | 8 | 13 | 33 | 50 | -17 | 29 | LXLL | 14 | 4 | 5 | 5 | 18 | 16 | 14 | 3 | 3 | 8 | 15 | 34 | |
| 9 | 1 | Chicago Fire | 27 | 7 | 6 | 14 | 34 | 42 | -8 | 27 | LXWL | 14 | 7 | 1 | 6 | 19 | 15 | 13 | 0 | 5 | 8 | 15 | 27 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 28 | 13 | 7 | 8 | 49 | 33 | +16 | 46 | LWWW | 14 | 11 | 2 | 1 | 36 | 9 | 14 | 2 | 5 | 7 | 13 | 24 | ||
| 2 | Vancouver Whitecaps | 27 | 14 | 3 | 10 | 38 | 28 | +10 | 45 | LWLW | 12 | 7 | 1 | 4 | 21 | 13 | 15 | 7 | 2 | 6 | 17 | 15 | ||
| 3 | 4 | Seattle Sounders | 28 | 13 | 2 | 13 | 34 | 31 | +3 | 41 | WWLW | 15 | 10 | 1 | 4 | 22 | 12 | 13 | 3 | 1 | 9 | 12 | 19 | |
| 4 | 1 | FC Dallas | 25 | 12 | 5 | 8 | 35 | 30 | +5 | 41 | WLLL | 13 | 9 | 2 | 2 | 23 | 12 | 12 | 3 | 3 | 6 | 12 | 18 | |
| 5 | 1 | Sporting Kansas City | 25 | 11 | 7 | 7 | 40 | 35 | +5 | 40 | LLLW | 13 | 8 | 4 | 1 | 23 | 15 | 12 | 3 | 3 | 6 | 17 | 20 | |
| 6 | 1 | Portland Timbers | 27 | 11 | 7 | 9 | 29 | 32 | -3 | 40 | LXWW | 13 | 7 | 5 | 1 | 19 | 9 | 14 | 4 | 2 | 8 | 10 | 23 | |
| 7 | 1 | San Jose Earthquakes | 27 | 11 | 5 | 11 | 33 | 31 | +2 | 38 | LWWW | 12 | 6 | 3 | 3 | 12 | 8 | 15 | 5 | 2 | 8 | 21 | 23 | |
| 8 | Houston Dynamo | 27 | 9 | 8 | 10 | 35 | 34 | +1 | 35 | WLXL | 13 | 7 | 3 | 3 | 24 | 15 | 14 | 2 | 5 | 7 | 11 | 19 | ||
| 9 | Colorado Rapids | 26 | 8 | 9 | 9 | 25 | 27 | -2 | 33 | WWWL | 14 | 5 | 4 | 5 | 17 | 19 | 12 | 3 | 5 | 4 | 8 | 8 | ||
| 10 | Real Salt Lake | 27 | 8 | 8 | 11 | 29 | 40 | -11 | 32 | LWLL | 14 | 6 | 6 | 2 | 19 | 12 | 13 | 2 | 2 | 9 | 10 | 28 | ||
| 18 | Kei KAMARA (Columbus Crew) | |
| 17 | Sebastian GIOVINCO (Toronto FC, 3p) | |
| 15 | Robbie KEANE (LA Galaxy, 4p) | |
| David VILLA (New York City, 5p) | ||
| 13 | +1 | Chris WONDOLOWSKI (San Jose Earthquakes, 5p) |
| +2 | Bradley WRIGHT-PHILLIPS (New York Red Bulls, 2p) | |
| 11 | Cyle LARIN (Orlando City) | |
| +2 | Obafemi MARTINS (Seattle Sounders) | |
| 10 | Fanendo ADI (Portland Timbers, 1p) | |
| Will BRUIN (Houston Dynamo) | ||
| Jozy ALTIDORE (Toronto FC, 3p) | ||
| 9 | Fabián CASTILLO (FC Dallas) | |
| Chris ROLFE (D.C. United, 3p) | ||
| Dominic DWYER (Sporting Kansas City) | ||
| Charlie DAVIES (New England Revolution) | ||
| Octavio RIVERO (Vancouver Whitecaps, 3p) | ||
| KAKÁ (Orlando City, 4p) | ||
| 8 | Krisztián NÉMETH (Sporting Kansas City) | |
| Ignacio PIATTI (Montréal Impact, 4p) | ||
| +1 | Clint DEMPSEY (Seattle Sounders, 1p) | |
| Benny FEILHABER (Sporting Kansas City, 4p) | ||
| Ethan FINLAY (Columbus Crew) |
| Sunday, 30 August 2015 | |||||
| New York Red Bulls | 3-0 | D.C. United | |||
| 33 | Sam | ||||
| 42 | Wright-Phillips | ||||
| 64 | Wright-Phillips | ||||
| Seattle Sounders | 2-1 | Portland Timbers | |||
| 6 | Martins | 58 | Jewsbury | ||
| 42(p) | Evans | ||||
| Saturday, 5 September 2015 | |||||
| New England Revolution | 3-0 | Orlando City | |||
| 43 | Fagúndez | ||||
| 84 | Agudelo | ||||
| 90 | Tierney | ||||
| Montréal Impact | 4-3 | Chicago Fire | |||
| 27 | Drogba | 36(p) | Larentowicz | ||
| 42 | Lefèvre | 44 | Gilberto | ||
| 61 | Drogba | 59 | Igboananike | ||
| 65 | Drogba | ||||
| Seattle Sounders | 2-1 | Toronto FC | |||
| 6 | Martins | 59 | Zavaleta | ||
| 77 | Dempsey | ||||
| San Jose Earthquakes | 1-2 | Philadelphia Union | |||
| 64(p) | Wondolowski | 74 | Casey | ||
| 86 | Casey | ||||