Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 320 | 875 | 2.73 | 171 | 53.44% | 71 | 22.19% | 78 | 24.38% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | New York Red Bulls | 32 | 16 | 6 | 10 | 56 | 41 | +15 | 54 | LWWL | 16 | 11 | 2 | 3 | 31 | 17 | 16 | 5 | 4 | 7 | 25 | 24 | ||
| 2 | 3 | Toronto FC | 32 | 15 | 4 | 13 | 57 | 54 | +3 | 49 | WWWW | 16 | 11 | 1 | 4 | 34 | 20 | 16 | 4 | 3 | 9 | 23 | 34 | |
| 3 | 1 | D.C. United | 32 | 14 | 6 | 12 | 39 | 40 | -1 | 48 | WLLX | 16 | 10 | 3 | 3 | 30 | 21 | 16 | 4 | 3 | 9 | 9 | 19 | |
| 4 | 1 | New England Revolution | 32 | 13 | 8 | 11 | 45 | 45 | +0 | 47 | LXLW | 16 | 9 | 6 | 1 | 27 | 11 | 16 | 4 | 2 | 10 | 18 | 34 | |
| 5 | 1 | Columbus Crew | 32 | 13 | 8 | 11 | 51 | 53 | -2 | 47 | LLWW | 16 | 8 | 4 | 4 | 33 | 25 | 16 | 5 | 4 | 7 | 18 | 28 | |
| 6 | Montréal Impact | 32 | 13 | 6 | 13 | 45 | 43 | +2 | 45 | WLLW | 16 | 10 | 2 | 4 | 30 | 16 | 16 | 3 | 4 | 9 | 15 | 27 | ||
| 7 | Orlando City | 32 | 11 | 8 | 13 | 44 | 54 | -10 | 41 | WWWW | 16 | 6 | 5 | 5 | 23 | 18 | 16 | 5 | 3 | 8 | 21 | 36 | ||
| 8 | Philadelphia Union | 32 | 9 | 7 | 16 | 40 | 51 | -11 | 34 | LXWL | 16 | 6 | 3 | 7 | 21 | 19 | 16 | 3 | 4 | 9 | 19 | 32 | ||
| 9 | Chicago Fire | 32 | 8 | 6 | 18 | 42 | 52 | -10 | 30 | WLLL | 16 | 8 | 1 | 7 | 22 | 17 | 16 | 0 | 5 | 11 | 20 | 35 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 3 | FC Dallas | 32 | 16 | 6 | 10 | 49 | 38 | +11 | 54 | WOWL | 16 | 12 | 2 | 2 | 31 | 14 | 16 | 4 | 4 | 8 | 18 | 24 | |
| 2 | 1 | LA Galaxy | 32 | 14 | 9 | 9 | 53 | 39 | +14 | 51 | XWLO | 16 | 12 | 3 | 1 | 39 | 11 | 16 | 2 | 6 | 8 | 14 | 28 | |
| 3 | 1 | Vancouver Whitecaps | 33 | 15 | 5 | 13 | 42 | 36 | +6 | 50 | LOXL | 16 | 8 | 2 | 6 | 24 | 18 | 17 | 7 | 3 | 7 | 18 | 18 | |
| 4 | 1 | Sporting Kansas City | 31 | 13 | 9 | 9 | 46 | 41 | +5 | 48 | WXLW | 15 | 9 | 5 | 1 | 27 | 17 | 16 | 4 | 4 | 8 | 19 | 24 | |
| 5 | Seattle Sounders | 32 | 14 | 5 | 13 | 40 | 34 | +6 | 47 | XXWX | 16 | 10 | 2 | 4 | 23 | 13 | 16 | 4 | 3 | 9 | 17 | 21 | ||
| 6 | 1 | Portland Timbers | 32 | 13 | 8 | 11 | 32 | 36 | -4 | 47 | WLWL | 16 | 7 | 6 | 3 | 19 | 12 | 16 | 6 | 2 | 8 | 13 | 24 | |
| 7 | 1 | San Jose Earthquakes | 32 | 12 | 8 | 12 | 39 | 37 | +2 | 44 | XWLX | 16 | 7 | 6 | 3 | 16 | 11 | 16 | 5 | 2 | 9 | 23 | 26 | |
| 8 | Houston Dynamo | 32 | 11 | 8 | 13 | 41 | 45 | -4 | 41 | LWWL | 16 | 9 | 3 | 4 | 29 | 20 | 16 | 2 | 5 | 9 | 12 | 25 | ||
| 9 | Real Salt Lake | 32 | 11 | 8 | 13 | 37 | 44 | -7 | 41 | LWLW | 16 | 7 | 6 | 3 | 22 | 13 | 16 | 4 | 2 | 10 | 15 | 31 | ||
| 10 | Colorado Rapids | 32 | 8 | 10 | 14 | 30 | 39 | -9 | 34 | LLLL | 17 | 5 | 5 | 7 | 19 | 23 | 15 | 3 | 5 | 7 | 11 | 16 | ||
| 22 | Kei KAMARA (Columbus Crew) | |
| +1 | Sebastian GIOVINCO (Toronto FC, 3p) | |
| 17 | +1 | Robbie KEANE (LA Galaxy, 4p) |
| David VILLA (New York City, 6p) | ||
| 16 | Chris WONDOLOWSKI (San Jose Earthquakes, 6p) | |
| 15 | Cyle LARIN (Orlando City) | |
| Bradley WRIGHT-PHILLIPS (New York Red Bulls, 2p) | ||
| 14 | Obafemi MARTINS (Seattle Sounders) | |
| 13 | +1 | Fanendo ADI (Portland Timbers, 2p) |
| 12 | Jozy ALTIDORE (Toronto FC, 3p) | |
| 11 | Dominic DWYER (Sporting Kansas City) | |
| Will BRUIN (Houston Dynamo) | ||
| 10 | Krisztián NÉMETH (Sporting Kansas City) | |
| Chris ROLFE (D.C. United, 4p) | ||
| +1 | Lloyd SAM (New York Red Bulls) | |
| Benny FEILHABER (Sporting Kansas City, 5p) | ||
| Octavio RIVERO (Vancouver Whitecaps, 3p) | ||
| David ACCAM (Chicago Fire) | ||
| 9 | Fabián CASTILLO (FC Dallas) | |
| Charlie DAVIES (New England Revolution) | ||
| C.J. SAPONG (Philadelphia Union) | ||
| Ethan FINLAY (Columbus Crew) | ||
| KAKÁ (Orlando City, 4p) | ||
| +2 | Didier DROGBA (Montréal Impact, 1p) |
| Sunday, 4 October 2015 | |||||
| FC Dallas | 4-1 | Houston Dynamo | |||
| 25(p) | Díaz | 36 | Clark | ||
| 51 | Texeira | ||||
| 53 | Acosta | ||||
| 90 | Texeira | ||||
| Colorado Rapids | 1-2 | Real Salt Lake | |||
| 16 | Doyle | 33 | Plata | ||
| 43 | Mulholland | ||||
| Seattle Sounders | 1-1 | LA Galaxy | |||
| 90 | Barrett | 36 | Keane | ||
| Wednesday, 7 October 2015 | |||||
| New York Red Bulls | 2-1 | Montréal Impact | |||
| 16(p) | Kljestan | 68(p) | Drogba | ||
| 39 | Sam | ||||
| Vancouver Whitecaps | 0-0 | FC Dallas | |||
| Saturday, 10 October 2015 | |||||
| Colorado Rapids | 0-1 | Montréal Impact | |||
| 15 | Drogba | ||||
| Wednesday, 14 October 2015 | |||||
| FC Dallas | 2-0 | Vancouver Whitecaps | |||
| 32 | Barrios | ||||
| 52 | Díaz | ||||
| Real Salt Lake | 0-1 | Portland Timbers | |||
| 54(p) | Adi | ||||
| Toronto FC | 2-1 | New York Red Bulls | |||
| 51 | Gomez | 86 | Wright-Phillips | ||
| 78 | Giovinco | ||||
