Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 290 | 792 | 2.73 | 154 | 53.10% | 66 | 22.76% | 70 | 24.14% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 2 | Columbus Crew | 30 | 13 | 8 | 9 | 49 | 49 | +0 | 47 | WWLW | 15 | 8 | 4 | 3 | 32 | 23 | 15 | 5 | 4 | 6 | 17 | 26 | |
| 2 | 2 | New England Revolution | 30 | 13 | 7 | 10 | 43 | 41 | +2 | 46 | LWWW | 15 | 9 | 5 | 1 | 26 | 10 | 15 | 4 | 2 | 9 | 17 | 31 | |
| 3 | 2 | New York Red Bulls | 27 | 13 | 6 | 8 | 47 | 32 | +15 | 45 | LWWL | 13 | 9 | 2 | 2 | 25 | 10 | 14 | 4 | 4 | 6 | 22 | 22 | |
| 4 | 2 | D.C. United | 30 | 13 | 6 | 11 | 37 | 37 | +0 | 45 | LXLL | 15 | 9 | 3 | 3 | 28 | 20 | 15 | 4 | 3 | 8 | 9 | 17 | |
| 5 | Toronto FC | 29 | 12 | 4 | 13 | 49 | 50 | -1 | 40 | WLLL | 13 | 8 | 1 | 4 | 26 | 16 | 16 | 4 | 3 | 9 | 23 | 34 | ||
| 6 | Montréal Impact | 27 | 10 | 6 | 11 | 38 | 38 | +0 | 36 | WXOW | 14 | 8 | 2 | 4 | 26 | 15 | 13 | 2 | 4 | 7 | 12 | 23 | ||
| 7 | 1 | Orlando City | 30 | 9 | 8 | 13 | 37 | 51 | -14 | 35 | WWLX | 15 | 5 | 5 | 5 | 21 | 17 | 15 | 4 | 3 | 8 | 16 | 34 | |
| 8 | 1 | Philadelphia Union | 29 | 8 | 6 | 15 | 36 | 47 | -11 | 30 | LWLW | 15 | 5 | 3 | 7 | 19 | 19 | 14 | 3 | 3 | 8 | 17 | 28 | |
| 9 | Chicago Fire | 29 | 7 | 6 | 16 | 36 | 46 | -10 | 27 | LLLX | 15 | 7 | 1 | 7 | 19 | 16 | 14 | 0 | 5 | 9 | 17 | 30 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Vancouver Whitecaps | 29 | 15 | 3 | 11 | 40 | 31 | +9 | 48 | LWLW | 14 | 8 | 1 | 5 | 23 | 16 | 15 | 7 | 2 | 6 | 17 | 15 | ||
| 2 | FC Dallas | 28 | 14 | 5 | 9 | 41 | 34 | +7 | 47 | LWWW | 14 | 10 | 2 | 2 | 25 | 13 | 14 | 4 | 3 | 7 | 16 | 21 | ||
| 3 | LA Galaxy | 30 | 13 | 8 | 9 | 49 | 36 | +13 | 47 | LOLW | 15 | 11 | 3 | 1 | 36 | 9 | 15 | 2 | 5 | 8 | 13 | 27 | ||
| 4 | Seattle Sounders | 30 | 14 | 3 | 13 | 38 | 32 | +6 | 45 | WXWW | 15 | 10 | 1 | 4 | 22 | 12 | 15 | 4 | 2 | 9 | 16 | 20 | ||
| 5 | Sporting Kansas City | 28 | 12 | 8 | 8 | 44 | 39 | +5 | 44 | WLOL | 14 | 9 | 4 | 1 | 26 | 16 | 14 | 3 | 4 | 7 | 18 | 23 | ||
| 6 | Portland Timbers | 28 | 11 | 8 | 9 | 29 | 32 | -3 | 41 | OLXW | 14 | 7 | 6 | 1 | 19 | 9 | 14 | 4 | 2 | 8 | 10 | 23 | ||
| 7 | San Jose Earthquakes | 30 | 11 | 7 | 12 | 37 | 36 | +1 | 40 | LXXL | 14 | 6 | 5 | 3 | 14 | 10 | 16 | 5 | 2 | 9 | 23 | 26 | ||
| 8 | 1 | Real Salt Lake | 29 | 10 | 8 | 11 | 35 | 41 | -6 | 38 | WWLW | 15 | 7 | 6 | 2 | 22 | 12 | 14 | 3 | 2 | 9 | 13 | 29 | |
| 9 | 1 | Houston Dynamo | 28 | 9 | 8 | 11 | 36 | 37 | -1 | 35 | LWLX | 14 | 7 | 3 | 4 | 25 | 18 | 14 | 2 | 5 | 7 | 11 | 19 | |
| 10 | Colorado Rapids | 29 | 8 | 10 | 11 | 27 | 33 | -6 | 34 | LXLW | 15 | 5 | 5 | 5 | 18 | 20 | 14 | 3 | 5 | 6 | 9 | 13 | ||
| 21 | +1 | Kei KAMARA (Columbus Crew) |
| 19 | +2 | Sebastian GIOVINCO (Toronto FC, 3p) |
| 16 | +1 | David VILLA (New York City, 5p) |
| 15 | +2 | Chris WONDOLOWSKI (San Jose Earthquakes, 6p) |
| Robbie KEANE (LA Galaxy, 4p) | ||
| 14 | Bradley WRIGHT-PHILLIPS (New York Red Bulls, 2p) | |
| 13 | +1 | Obafemi MARTINS (Seattle Sounders) |
| 11 | Cyle LARIN (Orlando City) | |
| 10 | +1 | Chris ROLFE (D.C. United, 4p) |
| Fanendo ADI (Portland Timbers, 1p) | ||
| +1 | Dominic DWYER (Sporting Kansas City) | |
| +2 | Benny FEILHABER (Sporting Kansas City, 5p) | |
| Will BRUIN (Houston Dynamo) | ||
| Octavio RIVERO (Vancouver Whitecaps, 3p) | ||
| Jozy ALTIDORE (Toronto FC, 3p) | ||
| 9 | +1 | Krisztián NÉMETH (Sporting Kansas City) |
| Fabián CASTILLO (FC Dallas) | ||
| Charlie DAVIES (New England Revolution) | ||
| +1 | Ethan FINLAY (Columbus Crew) | |
| KAKÁ (Orlando City, 4p) | ||
| 8 | Ignacio PIATTI (Montréal Impact, 4p) | |
| Clint DEMPSEY (Seattle Sounders, 1p) | ||
| +1 | Javier MORALES (Real Salt Lake, 2p) | |
| C.J. SAPONG (Philadelphia Union) | ||
| David ACCAM (Chicago Fire) |
| Sunday, 13 September 2015 | |||||
| Toronto FC | 1-3 | New England Revolution | |||
| 55 | Findley | 4(og) | Perquis | ||
| 39 | Fagúndez | ||||
| 71 | Rowe | ||||
| Orlando City | 3-1 | Sporting Kansas City | |||
| 3 | Winter | 59 | Németh | ||
| 66 | Róchez | ||||
| 72 | Winter | ||||
| Wednesday, 16 September 2015 | |||||
| New England Revolution | 2-1 | New York Red Bulls | |||
| 2 | Fagúndez | 6 | Grella | ||
| 65 | Rowe | ||||
| San Jose Earthquakes | 1-1 | Montréal Impact | |||
| 35 | Wondolowski | 65 | Bekker | ||
| New York City | 2-0 | Toronto FC | |||
| 20 | Lampard | ||||
| 77 | Mullins | ||||
| Friday, 18 September 2015 | |||||
| Sporting Kansas City | 3-1 | FC Dallas | |||
| 65 | Feilhaber | 80 | Ulloa | ||
| 76(p) | Feilhaber | ||||
| 83 | Dwyer | ||||
| Saturday, 19 September 2015 | |||||
| D.C. United | 1-2 | Columbus Crew | |||
| 68(p) | Rolfe | 27 | Finlay | ||
| 49 | Kamara | ||||
| Chicago Fire | 0-1 | Orlando City | |||
| 86 | Róchez | ||||
| Vancouver Whitecaps | 0-3 | Seattle Sounders | |||
| 45 | Ivanschitz | ||||
| 71 | Pineda | ||||
| 87 | Martins | ||||
| Montréal Impact | 3-0 | New England Revolution | |||
| 5 | Venegas | ||||
| 60 | Drogba | ||||
| 76 | Duka | ||||
| Real Salt Lake | 3-0 | LA Galaxy | |||
| 3 | Sandoval | ||||
| 28(p) | Morales | ||||
| 53 | Sandoval | ||||
| Toronto FC | 3-1 | Colorado Rapids | |||
| 14 | Giovinco | 40 | Powers | ||
| 18 | Giovinco | ||||
| 38 | Perquis | ||||
| New York City | 3-2 | San Jose Earthquakes | |||
| 51 | Grabavoy | 72 | Amarikwa | ||
| 63 | Grabavoy | 76(p) | Wondolowski | ||
| 65 | Villa | ||||
