| ROUND | R1 | QF | SF | F | |||
| l1 | l2 | l1 | l2 | l1 | l2 | ||
| Season archive |
| Tuesday, 4 May 2021 | ||||||
| qfl2 |  Cruz Azul | 1-0 | Toronto FC | 4-1 | ||
| 28 | Angulo | |||||
| qfl2 | Philadelphia Union | 1-1 | Atlanta United | 4-1 | ||
| 88 | Przybyłko | 45 | Sosa | |||
| Wednesday, 5 May 2021 | ||||||
| qfl2 | América | 3-1 | Portland Timbers | 4-2 | ||
| 21 | Viñas | 64(p) | Valeri | |||
| 59(p) | Viñas | |||||
| 70 | Suárez | |||||
| qfl2 | Monterrey | 3-0 | Columbus Crew | 5-2 | ||
| 3 | Meza | |||||
| 26 | Meza | |||||
| 71 | Layún | |||||
| 5 | +1 | Kacper PRZYBYŁKO (Philadelphia Union) |
| 4 | +1 | Brayan ANGULO (Cruz Azul) |
| 3 | +2 | Federico VIÑAS (América, 1p) |
| Yimmi CHARÁ (Portland Timbers) | ||
| 2 | Vincent JANSSEN (Monterrey) | |
| Fernando NAVARRO (León) | ||
| Walter MONTOYA (Cruz Azul) | ||
| +2 | Maximiliano MEZA (Monterrey) | |
| José ALVARADO (Monterrey) | ||
| Gyasi ZARDES (Columbus Crew) | ||
| Jamiro MONTEIRO (Philadelphia Union, 1p) | ||
| +1 | Diego VALERI (Portland Timbers, 1p) | |
| Felipe MORA (Portland Timbers, 1p) | ||
| Anthony FONTANA (Philadelphia Union) |
