Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 26 | 79 | 3.03 | 12 | 46.15% | 9 | 34.62% | 5 | 19.23% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | CF Montréal | 2 | 1 | 1 | 0 | 6 | 4 | +2 | 4 | XW-- | 1 | 1 | 0 | 0 | 4 | 2 | 1 | 0 | 1 | 0 | 2 | 2 | ||
| 2 | 8 | Atlanta United | 2 | 1 | 1 | 0 | 3 | 1 | +2 | 4 | WO-- | 1 | 1 | 0 | 0 | 3 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | |
| 3 | 2 | New England Revolution | 2 | 1 | 1 | 0 | 3 | 2 | +1 | 4 | WX-- | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 2 | 2 | |
| 4 | 9 | New York City | 2 | 1 | 0 | 1 | 6 | 2 | +4 | 3 | WL-- | 1 | 1 | 0 | 0 | 5 | 0 | 1 | 0 | 0 | 1 | 1 | 2 | |
| 5 | 6 | Inter Miami | 2 | 1 | 0 | 1 | 4 | 4 | +0 | 3 | WL-- | 1 | 0 | 0 | 1 | 2 | 3 | 1 | 1 | 0 | 0 | 2 | 1 | |
| 6 | 4 | D.C. United | 2 | 1 | 0 | 1 | 2 | 2 | +0 | 3 | LW-- | 1 | 1 | 0 | 0 | 2 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | |
| 7 | 3 | Nashville | 2 | 0 | 2 | 0 | 4 | 4 | +0 | 2 | XX-- | 2 | 0 | 2 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | |
| 8 | 1 | Orlando City | 2 | 0 | 2 | 0 | 1 | 1 | +0 | 2 | XO-- | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | |
| 9 | Columbus Crew | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | O--- | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 10 | 2 | Philadelphia Union | 2 | 0 | 1 | 1 | 1 | 2 | -1 | 1 | LO-- | 1 | 0 | 0 | 1 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | |
| 11 | 3 | Toronto FC | 2 | 0 | 1 | 1 | 4 | 6 | -2 | 1 | XL-- | 1 | 0 | 1 | 0 | 2 | 2 | 1 | 0 | 0 | 1 | 2 | 4 | |
| 12 | 9 | Chicago Fire | 2 | 0 | 1 | 1 | 3 | 5 | -2 | 1 | LX-- | 1 | 0 | 1 | 0 | 2 | 2 | 1 | 0 | 0 | 1 | 1 | 3 | |
| 13 | 7 | FC Cincinnati | 2 | 0 | 1 | 1 | 2 | 7 | -5 | 1 | LX-- | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 2 | 7 | |
| 14 | 2 | New York Red Bulls | 2 | 0 | 0 | 2 | 3 | 5 | -2 | 0 | LL-- | 1 | 0 | 0 | 1 | 1 | 2 | 1 | 0 | 0 | 1 | 2 | 3 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 2 | LA Galaxy | 2 | 2 | 0 | 0 | 6 | 4 | +2 | 6 | WW-- | 1 | 1 | 0 | 0 | 3 | 2 | 1 | 1 | 0 | 0 | 3 | 2 | |
| 2 | 1 | Seattle Sounders | 2 | 1 | 1 | 0 | 5 | 1 | +4 | 4 | XW-- | 1 | 1 | 0 | 0 | 4 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | |
| 3 | 1 | Los Angeles | 2 | 1 | 1 | 0 | 3 | 1 | +2 | 4 | XW-- | 2 | 1 | 1 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| 4 | 2 | Vancouver Whitecaps | 2 | 1 | 1 | 0 | 3 | 2 | +1 | 4 | XW-- | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 2 | 2 | |
| 5 | Sporting Kansas City | 2 | 1 | 1 | 0 | 3 | 2 | +1 | 4 | XW-- | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 2 | 1 | ||
| 6 | 4 | San Jose Earthquakes | 2 | 1 | 0 | 1 | 4 | 3 | +1 | 3 | WL-- | 1 | 1 | 0 | 0 | 3 | 1 | 1 | 0 | 0 | 1 | 1 | 2 | |
| 7 | 2 | Real Salt Lake | 1 | 1 | 0 | 0 | 2 | 1 | +1 | 3 | W--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | |
| 8 | 4 | Houston Dynamo | 2 | 1 | 0 | 1 | 3 | 3 | +0 | 3 | LW-- | 1 | 1 | 0 | 0 | 2 | 1 | 1 | 0 | 0 | 1 | 1 | 2 | |
| 9 | 3 | Austin FC | 2 | 1 | 0 | 1 | 3 | 3 | +0 | 3 | WL-- | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 3 | 3 | |
| 10 | 1 | Portland Timbers | 2 | 1 | 0 | 1 | 2 | 2 | +0 | 3 | WL-- | 1 | 1 | 0 | 0 | 2 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | |
| 11 | 4 | FC Dallas | 2 | 0 | 1 | 1 | 1 | 3 | -2 | 1 | LO-- | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 3 | |
| 12 | 4 | Colorado Rapids | 2 | 0 | 1 | 1 | 1 | 3 | -2 | 1 | LO-- | 1 | 0 | 0 | 1 | 1 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | |
| 13 | Minnesota United | 2 | 0 | 0 | 2 | 1 | 6 | -5 | 0 | LL-- | 1 | 0 | 0 | 1 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | 4 | ||
| 5 | +3 | Javier HERNÁNDEZ (LA Galaxy) |
| 2 | +1 | Mason TOYE (CF Montréal) |
| +1 | Valentín CASTELLANOS (New York City) | |
| Raúl RUIDÍAZ (Seattle Sounders) | ||
| +1 | Luka STOJANOVIĆ (Chicago Fire) | |
| +2 | Anderson JULIO (Real Salt Lake) | |
| +2 | Cecilio DOMÍNGUEZ (Austin FC) | |
| +2 | Jesús MEDINA (New York City) | |
| +1 | Jhonder CÁDIZ (Nashville) | |
| +1 | Gonzalo HIGUAÍN (Inter Miami, 1p) |
| Friday, 23 April 2021 | |||||
| Sporting Kansas City | 1-1 | Orlando City | |||
| 45 | Busio | 79 | Nani | ||
| Saturday, 24 April 2021 | |||||
| Colorado Rapids | 1-3 | Austin FC | |||
| 36 | André Bava | 60 | Fagúndez | ||
| 67 | Domínguez | ||||
| 71 | Domínguez | ||||
| New England Revolution | 1-0 | D.C. United | |||
| 48(og) | Hines-Ike | ||||
| Portland Timbers | 2-1 | Houston Dynamo | |||
| 6 | Asprilla | 28(og) | Paredes | ||
| 73 | Paredes | ||||
| Toronto FC | 2-2 | Vancouver Whitecaps | |||
| 7 | Singh | 55(p) | Dájome | ||
| 82 | Osorio | 70 | Rose | ||
| San Jose Earthquakes | 3-1 | FC Dallas | |||
| 34(p) | Alanís | 79 | Pepi | ||
| 49 | Espinoza | ||||
| 59 | Cowell | ||||
| Philadelphia Union | 1-2 | Inter Miami | |||
| 54 | Monteiro | 73 | Higuaín | ||
| 83 | Higuaín | ||||
| Minnesota United | 1-2 | Real Salt Lake | |||
| 86 | Lod | 31 | Julio | ||
| 41 | Julio | ||||
| Los Angeles | 1-1 | Seattle Sounders | |||
| 2 | Atuesta | 54 | Smith | ||
| Nashville | 2-2 | CF Montréal | |||
| 54 | Cádiz | 13 | Toye | ||
| 77 | Mukhtar | 42 | Brault-Guillard | ||
| New York City | 5-0 | FC Cincinnati | |||
| 7 | Medina | ||||
| 53(og) | Hagglund | ||||
| 57 | Þórarinsson | ||||
| 67 | Castellanos | ||||
| 83 | Medina | ||||
| Atlanta United | 3-1 | Chicago Fire | |||
| 23 | Barco | 46 | Stojanović | ||
| 66(og) | Kappelhof | ||||
| 85 | Hyndman | ||||
| Sunday, 25 April 2021 | |||||
| LA Galaxy | 3-2 | New York Red Bulls | |||
| 9 | Hernández | 26 | Gutman | ||
| 41 | Hernández | 63 | Cásseres | ||
| 60 | Hernández | ||||
