Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 288 | 811 | 2.81 | 138 | 47.92% | 73 | 25.35% | 77 | 26.74% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Philadelphia Union | 21 | 10 | 9 | 2 | 33 | 15 | +18 | 39 | WWWO | 11 | 6 | 5 | 0 | 20 | 6 | 10 | 4 | 4 | 2 | 13 | 9 | ||
| 2 | New York City | 20 | 11 | 5 | 4 | 39 | 21 | +18 | 38 | WWWX | 11 | 7 | 3 | 1 | 28 | 12 | 9 | 4 | 2 | 3 | 11 | 9 | ||
| 3 | New York Red Bulls | 21 | 9 | 6 | 6 | 30 | 22 | +8 | 33 | LXWW | 10 | 3 | 4 | 3 | 14 | 11 | 11 | 6 | 2 | 3 | 16 | 11 | ||
| 4 | CF Montréal | 20 | 10 | 2 | 8 | 34 | 35 | -1 | 32 | WLLW | 10 | 6 | 0 | 4 | 18 | 14 | 10 | 4 | 2 | 4 | 16 | 21 | ||
| 5 | Orlando City | 21 | 8 | 6 | 7 | 26 | 30 | -4 | 30 | XXWL | 10 | 5 | 0 | 5 | 15 | 19 | 11 | 3 | 6 | 2 | 11 | 11 | ||
| 6 | 2 | Columbus Crew | 20 | 7 | 8 | 5 | 27 | 22 | +5 | 29 | WXWO | 9 | 4 | 2 | 3 | 12 | 7 | 11 | 3 | 6 | 2 | 15 | 15 | |
| 7 | 1 | FC Cincinnati | 21 | 7 | 6 | 8 | 32 | 37 | -5 | 27 | LXXX | 10 | 3 | 3 | 4 | 19 | 18 | 11 | 4 | 3 | 4 | 13 | 19 | |
| 8 | 1 | Charlotte FC | 21 | 8 | 2 | 11 | 25 | 27 | -2 | 26 | LWWL | 10 | 7 | 0 | 3 | 15 | 7 | 11 | 1 | 2 | 8 | 10 | 20 | |
| 9 | 2 | Inter Miami | 20 | 7 | 4 | 9 | 22 | 31 | -9 | 25 | WLLX | 11 | 6 | 2 | 3 | 18 | 16 | 9 | 1 | 2 | 6 | 4 | 15 | |
| 10 | 1 | New England Revolution | 20 | 6 | 7 | 7 | 32 | 34 | -2 | 25 | LLXO | 10 | 4 | 4 | 2 | 15 | 12 | 10 | 2 | 3 | 5 | 17 | 22 | |
| 11 | 1 | Atlanta United | 20 | 6 | 6 | 8 | 29 | 31 | -2 | 24 | XWLX | 11 | 5 | 4 | 2 | 20 | 15 | 9 | 1 | 2 | 6 | 9 | 16 | |
| 12 | Chicago Fire | 21 | 6 | 5 | 10 | 21 | 27 | -6 | 23 | WWLL | 11 | 5 | 3 | 3 | 12 | 8 | 10 | 1 | 2 | 7 | 9 | 19 | ||
| 13 | Toronto FC | 21 | 5 | 4 | 12 | 26 | 39 | -13 | 19 | LLXL | 11 | 5 | 1 | 5 | 16 | 19 | 10 | 0 | 3 | 7 | 10 | 20 | ||
| 14 | D.C. United | 19 | 5 | 3 | 11 | 25 | 41 | -16 | 18 | LXLW | 10 | 3 | 2 | 5 | 15 | 17 | 9 | 2 | 1 | 6 | 10 | 24 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 1 | Los Angeles | 20 | 13 | 3 | 4 | 40 | 22 | +18 | 42 | WWLW | 11 | 8 | 2 | 1 | 26 | 12 | 9 | 5 | 1 | 3 | 14 | 10 | |
| 2 | 1 | Austin FC | 21 | 12 | 5 | 4 | 42 | 24 | +18 | 41 | XWWW | 9 | 5 | 3 | 1 | 22 | 8 | 12 | 7 | 2 | 3 | 20 | 16 | |
| 3 | 1 | Real Salt Lake | 21 | 9 | 6 | 6 | 28 | 26 | +2 | 33 | WLXL | 10 | 7 | 3 | 0 | 18 | 6 | 11 | 2 | 3 | 6 | 10 | 20 | |
| 4 | 1 | Minnesota United | 21 | 9 | 4 | 8 | 29 | 25 | +4 | 31 | WXWW | 11 | 5 | 3 | 3 | 16 | 10 | 10 | 4 | 1 | 5 | 13 | 15 | |
| 5 | 2 | Nashville | 21 | 8 | 6 | 7 | 27 | 27 | +0 | 30 | LWLX | 9 | 3 | 4 | 2 | 12 | 10 | 12 | 5 | 2 | 5 | 15 | 17 | |
| 6 | FC Dallas | 21 | 7 | 8 | 6 | 31 | 25 | +6 | 29 | XLXX | 11 | 5 | 3 | 3 | 17 | 11 | 10 | 2 | 5 | 3 | 14 | 14 | ||
| 7 | LA Galaxy | 20 | 8 | 3 | 9 | 28 | 27 | +1 | 27 | LLLW | 11 | 5 | 1 | 5 | 18 | 16 | 9 | 3 | 2 | 4 | 10 | 11 | ||
| 8 | 1 | Portland Timbers | 21 | 6 | 9 | 6 | 33 | 30 | +3 | 27 | XWXW | 10 | 4 | 4 | 2 | 18 | 12 | 11 | 2 | 5 | 4 | 15 | 18 | |
| 9 | 1 | Seattle Sounders | 20 | 8 | 2 | 10 | 26 | 24 | +2 | 26 | LLLW | 10 | 5 | 1 | 4 | 17 | 12 | 10 | 3 | 1 | 6 | 9 | 12 | |
| 10 | Vancouver Whitecaps | 21 | 7 | 5 | 9 | 23 | 34 | -11 | 26 | XXLW | 10 | 5 | 3 | 2 | 13 | 11 | 11 | 2 | 2 | 7 | 10 | 23 | ||
| 11 | Houston Dynamo | 21 | 7 | 4 | 10 | 27 | 29 | -2 | 25 | WLXL | 11 | 4 | 4 | 3 | 15 | 12 | 10 | 3 | 0 | 7 | 12 | 17 | ||
| 12 | 1 | Colorado Rapids | 20 | 6 | 6 | 8 | 24 | 27 | -3 | 24 | WXXL | 11 | 6 | 3 | 2 | 17 | 8 | 9 | 0 | 3 | 6 | 7 | 19 | |
| 13 | 1 | San Jose Earthquakes | 20 | 5 | 7 | 8 | 33 | 41 | -8 | 22 | LWXW | 10 | 4 | 4 | 2 | 20 | 19 | 10 | 1 | 3 | 6 | 13 | 22 | |
| 14 | Sporting Kansas City | 22 | 5 | 5 | 12 | 19 | 38 | -19 | 20 | LXWL | 9 | 3 | 2 | 4 | 8 | 9 | 13 | 2 | 3 | 8 | 11 | 29 | ||
| 13 | +1 | Valentín CASTELLANOS (New York City, 5p) |
| 12 | +1 | Hany MUKHTAR (Nashville, 2p) |
| 11 | Jeremy EBOBISSE (San Jose Earthquakes, 1p) | |
| Jesús FERREIRA (FC Dallas) | ||
| Sebastián DRIUSSI (Austin FC, 2p) | ||
| 10 | Taxiarchis FOUNTAS (D.C. United) | |
| Brandon VÁZQUEZ (FC Cincinnati) | ||
| 9 | Lewis MORGAN (New York Red Bulls, 4p) | |
| +1 | Dániel GAZDAG (Philadelphia Union, 3p) | |
| +1 | Paul ARRIOLA (FC Dallas) | |
| +2 | Emanuel REYNOSO (Minnesota United, 2p) | |
| +1 | Diego RUBIO (Colorado Rapids, 2p) | |
| 8 | Dejan JOVELJIĆ (LA Galaxy, 1p) | |
| +1 | Cristian ARANGO (Los Angeles, 1p) | |
| Leonardo CAMPANA (Inter Miami) | ||
| Jesús JIMÉNEZ (Toronto FC) | ||
| 7 | Jarosław NIEZGODA (Portland Timbers) | |
| Maximiliano URRUTI (Austin FC) | ||
| Julián CARRANZA (Philadelphia Union, 1p) | ||
| Javier HERNÁNDEZ (LA Galaxy) | ||
| Djordje MIHAILOVIC (CF Montréal) | ||
| +1 | Sebastián FERREIRA (Houston Dynamo) | |
| Ercan KARA (Orlando City) | ||
| Adam BUKSA (New England Revolution) | ||
| Ola KAMARA (D.C. United, 1p) | ||
| +1 | Gustavo BOU (New England Revolution, 1p) | |
| Rommel QUIOTO (CF Montréal, 2p) | ||
| Darwin QUINTERO (Houston Dynamo, 1p) |
| Saturday, 16 July 2022 | |||||
| FC Dallas | 1-1 | Austin FC | |||
| 42 | Arriola | 79 | Fagúndez | ||
| Colorado Rapids | 2-0 | LA Galaxy | |||
| 20 | Rubio | ||||
| 75 | Zardes | ||||
| Chicago Fire | 1-0 | Seattle Sounders | |||
| 23 | Czichos | ||||
| CF Montréal | 1-0 | Toronto FC | |||
| 69(og) | MacNaughton | ||||
| Philadelphia Union | 2-1 | New England Revolution | |||
| 75 | Uhre | 61 | Bou | ||
| 79(p) | Gazdag | ||||
| Minnesota United | 2-0 | D.C. United | |||
| 13 | Reynoso | ||||
| 50 | Reynoso | ||||
| Inter Miami | 3-2 | Charlotte FC | |||
| 59 | Taylor | 1 | Reyna | ||
| 72 | Higuaín | 42 | Reyna | ||
| 90 | Rodríguez | ||||
| Sunday, 17 July 2022 | |||||
| New York Red Bulls | 0-1 | New York City | |||
| 69 | Castellanos | ||||
| Columbus Crew | 2-0 | FC Cincinnati | |||
| 16 | Cucho | ||||
| 86(p) | Zelarayán | ||||
| Portland Timbers | 1-1 | Vancouver Whitecaps | |||
| 82(p) | Mora | 32 | White | ||
| Real Salt Lake | 3-0 | Sporting Kansas City | |||
| 50 | Córdova | ||||
| 64 | Ruíz | ||||
| 71 | Savarino | ||||
| San Jose Earthquakes | 1-2 | Houston Dynamo | |||
| 53 | Yueill | 71 | Ferreira | ||
| 76 | Úlfarsson | ||||
| Nashville | 1-2 | Los Angeles | |||
| 43(p) | Mukhtar | 27 | Arango | ||
| 46 | Cifuentes | ||||
| Atlanta United | 1-1 | Orlando City | |||
| 71 | Sánchez | 10 | Pereyra | ||
