Primera División| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | Apertura |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | Clausura |
| Season archive |
| Friday, 10 December 2021 | |||||
| 12 | River Plate | - | Peñarol | ||
| 12 | Liverpool | - | Torque | ||
| 12 | Deportivo Maldonado | - | Nacional | ||
| 12 | Cerrito | - | Villa Española | ||
| 12 | Plaza Colonia | - | Fénix | ||
| 12 | Progreso | - | Wanderers | ||
| 12 | Sud América | - | Boston River | ||
| 12 | Cerro Largo | - | Rentistas | ||
